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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3A
All Species:
30.91
Human Site:
S1364
Identified Species:
40
UniProt:
Q14152
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14152
NP_003741.1
1382
166569
S1364
R
A
E
K
D
R
E
S
L
R
R
T
K
N
E
Chimpanzee
Pan troglodytes
XP_001153575
1382
166541
S1364
R
A
E
K
D
R
E
S
L
R
R
T
K
N
E
Rhesus Macaque
Macaca mulatta
XP_001102472
1228
147070
S1210
R
A
E
K
D
R
E
S
L
R
R
T
K
N
E
Dog
Lupus familis
XP_852131
1350
163016
S1332
R
A
E
K
D
R
E
S
L
R
R
T
K
N
E
Cat
Felis silvestris
Mouse
Mus musculus
P23116
1344
161918
S1326
R
A
E
K
D
R
E
S
L
R
R
T
K
N
E
Rat
Rattus norvegicus
Q1JU68
1354
163177
S1336
R
A
E
K
D
R
E
S
L
R
R
T
K
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514639
1362
163866
T1344
R
S
E
K
E
R
E
T
L
R
R
T
K
N
E
Chicken
Gallus gallus
XP_421787
1505
177889
P1487
K
T
E
K
E
R
E
P
A
R
R
T
K
N
E
Frog
Xenopus laevis
A2VD00
1424
168482
A1406
E
K
K
E
E
K
D
A
P
R
R
P
K
L
E
Zebra Danio
Brachydanio rerio
Q6PCR7
1267
151273
N1249
R
S
D
K
D
K
E
N
P
R
R
T
K
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN25
1140
133861
A1121
P
A
A
K
R
D
Q
A
Q
E
K
E
N
K
A
Honey Bee
Apis mellifera
XP_397439
1143
134949
S1123
L
S
E
Y
T
N
K
S
L
G
K
K
H
K
N
Nematode Worm
Caenorhab. elegans
P34339
1076
124390
R1059
R
R
D
G
P
P
P
R
S
N
N
T
G
N
T
Sea Urchin
Strong. purpuratus
XP_798957
1284
149812
N1265
K
G
G
E
R
G
G
N
Q
Q
R
D
E
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XHR2
962
111545
S944
D
T
D
R
W
R
G
S
R
F
P
S
N
S
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD55
987
114281
G966
G
G
D
R
W
G
S
G
P
R
G
S
D
D
R
Baker's Yeast
Sacchar. cerevisiae
P38249
964
110326
K947
T
P
S
S
G
P
K
K
M
T
M
A
E
K
L
Red Bread Mold
Neurospora crassa
Q7RWT1
1007
114509
K990
V
P
P
A
E
P
L
K
A
S
G
A
P
G
K
Conservation
Percent
Protein Identity:
100
99.9
86.5
94.2
N.A.
93.1
93.1
N.A.
88.2
75.6
72.1
75
N.A.
41.5
42.1
31.4
45.4
Protein Similarity:
100
99.9
87.4
95.9
N.A.
95.5
95.5
N.A.
93.1
81.7
81.4
82.1
N.A.
58
58.5
48.3
62.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
66.6
26.6
66.6
N.A.
13.3
20
20
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
80
66.6
93.3
N.A.
33.3
40
26.6
46.6
Percent
Protein Identity:
N.A.
27.2
N.A.
27.1
23.3
28.2
Protein Similarity:
N.A.
43.8
N.A.
44.6
41
43.6
P-Site Identity:
N.A.
13.3
N.A.
6.6
0
0
P-Site Similarity:
N.A.
40
N.A.
33.3
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
6
6
0
0
0
12
12
0
0
12
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
23
0
39
6
6
0
0
0
0
6
6
6
0
% D
% Glu:
6
0
50
12
23
0
50
0
0
6
0
6
12
0
56
% E
% Phe:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% F
% Gly:
6
12
6
6
6
12
12
6
0
6
12
0
6
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
6
6
56
0
12
12
12
0
0
12
6
56
17
12
% K
% Leu:
6
0
0
0
0
0
6
0
45
0
0
0
0
6
6
% L
% Met:
0
0
0
0
0
0
0
0
6
0
6
0
0
0
0
% M
% Asn:
0
0
0
0
0
6
0
12
0
6
6
0
12
56
6
% N
% Pro:
6
12
6
0
6
17
6
6
17
0
6
6
6
6
0
% P
% Gln:
0
0
0
0
0
0
6
0
12
6
0
0
0
0
0
% Q
% Arg:
50
6
0
12
12
50
0
6
6
62
62
0
0
0
6
% R
% Ser:
0
17
6
6
0
0
6
45
6
6
0
12
0
6
0
% S
% Thr:
6
12
0
0
6
0
0
6
0
6
0
56
0
0
12
% T
% Val:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _