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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3A
All Species:
27.58
Human Site:
S888
Identified Species:
35.69
UniProt:
Q14152
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14152
NP_003741.1
1382
166569
S888
S
S
L
S
R
K
D
S
R
W
G
D
R
D
S
Chimpanzee
Pan troglodytes
XP_001153575
1382
166541
S888
S
S
L
S
R
K
D
S
R
W
G
D
R
D
S
Rhesus Macaque
Macaca mulatta
XP_001102472
1228
147070
S724
S
S
L
S
R
K
D
S
R
W
G
D
R
D
S
Dog
Lupus familis
XP_852131
1350
163016
S888
D
P
L
S
R
K
D
S
R
W
G
D
R
D
S
Cat
Felis silvestris
Mouse
Mus musculus
P23116
1344
161918
S888
D
P
L
S
R
K
D
S
R
W
G
D
R
D
S
Rat
Rattus norvegicus
Q1JU68
1354
163177
S888
D
P
L
S
R
K
D
S
R
W
G
D
R
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514639
1362
163866
S910
D
P
L
S
R
K
D
S
R
W
G
D
R
D
S
Chicken
Gallus gallus
XP_421787
1505
177889
R1020
P
F
S
R
K
E
S
R
W
G
D
R
G
E
S
Frog
Xenopus laevis
A2VD00
1424
168482
T888
D
S
F
R
K
Q
D
T
P
S
R
W
G
D
R
Zebra Danio
Brachydanio rerio
Q6PCR7
1267
151273
N884
R
A
P
E
E
K
P
N
K
E
W
A
E
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN25
1140
133861
A836
A
A
E
E
R
A
A
A
E
A
R
R
L
E
R
Honey Bee
Apis mellifera
XP_397439
1143
134949
E842
E
E
R
A
K
R
E
E
E
E
R
L
R
R
A
Nematode Worm
Caenorhab. elegans
P34339
1076
124390
V775
T
F
D
W
V
E
S
V
K
I
D
N
Q
E
T
Sea Urchin
Strong. purpuratus
XP_798957
1284
149812
E862
I
A
R
L
R
E
I
E
E
K
R
M
K
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XHR2
962
111545
R690
D
Y
L
E
R
A
K
R
Q
E
E
A
P
L
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD55
987
114281
R709
L
I
E
A
A
Y
Q
R
R
L
V
E
E
R
E
Baker's Yeast
Sacchar. cerevisiae
P38249
964
110326
A689
V
Y
I
D
P
N
E
A
K
S
L
D
L
D
T
Red Bread Mold
Neurospora crassa
Q7RWT1
1007
114509
S736
P
F
Y
E
S
F
R
S
D
L
H
E
R
R
R
Conservation
Percent
Protein Identity:
100
99.9
86.5
94.2
N.A.
93.1
93.1
N.A.
88.2
75.6
72.1
75
N.A.
41.5
42.1
31.4
45.4
Protein Similarity:
100
99.9
87.4
95.9
N.A.
95.5
95.5
N.A.
93.1
81.7
81.4
82.1
N.A.
58
58.5
48.3
62.1
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
86.6
6.6
20
6.6
N.A.
6.6
6.6
0
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
86.6
26.6
40
26.6
N.A.
33.3
40
46.6
40
Percent
Protein Identity:
N.A.
27.2
N.A.
27.1
23.3
28.2
Protein Similarity:
N.A.
43.8
N.A.
44.6
41
43.6
P-Site Identity:
N.A.
13.3
N.A.
6.6
13.3
13.3
P-Site Similarity:
N.A.
20
N.A.
20
46.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
17
0
12
6
12
6
12
0
6
0
12
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
6
6
0
0
45
0
6
0
12
45
0
56
0
% D
% Glu:
6
6
12
23
6
17
12
12
17
17
6
12
12
17
12
% E
% Phe:
0
17
6
0
0
6
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
6
39
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% H
% Ile:
6
6
6
0
0
0
6
0
0
6
0
0
0
0
6
% I
% Lys:
0
0
0
0
17
45
6
0
17
6
0
0
6
0
0
% K
% Leu:
6
0
45
6
0
0
0
0
0
12
6
6
12
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% M
% Asn:
0
0
0
0
0
6
0
6
0
0
0
6
0
0
0
% N
% Pro:
12
23
6
0
6
0
6
0
6
0
0
0
6
0
0
% P
% Gln:
0
0
0
0
0
6
6
0
6
0
0
0
6
0
0
% Q
% Arg:
6
0
12
12
56
6
6
17
45
0
23
12
50
23
17
% R
% Ser:
17
23
6
39
6
0
12
45
0
12
0
0
0
0
45
% S
% Thr:
6
0
0
0
0
0
0
6
0
0
0
0
0
0
17
% T
% Val:
6
0
0
0
6
0
0
6
0
0
6
0
0
0
0
% V
% Trp:
0
0
0
6
0
0
0
0
6
39
6
6
0
0
0
% W
% Tyr:
0
12
6
0
0
6
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _