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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3A
All Species:
28.79
Human Site:
S907
Identified Species:
37.25
UniProt:
Q14152
Number Species:
17
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14152
NP_003741.1
1382
166569
S907
R
K
G
P
E
A
D
S
E
W
R
R
G
P
P
Chimpanzee
Pan troglodytes
XP_001153575
1382
166541
S907
R
K
G
P
E
A
D
S
E
W
R
R
G
P
P
Rhesus Macaque
Macaca mulatta
XP_001102472
1228
147070
S743
R
K
G
P
E
A
D
S
E
W
R
R
G
P
P
Dog
Lupus familis
XP_852131
1350
163016
S907
R
K
G
P
E
V
D
S
E
W
R
R
G
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P23116
1344
161918
S907
R
K
G
P
E
A
D
S
E
W
R
R
G
P
P
Rat
Rattus norvegicus
Q1JU68
1354
163177
S907
R
K
G
P
E
A
D
S
E
W
R
R
G
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514639
1362
163866
A929
R
K
S
A
E
P
E
A
E
W
R
R
G
P
P
Chicken
Gallus gallus
XP_421787
1505
177889
S1039
R
R
G
G
E
T
E
S
E
W
R
R
A
P
V
Frog
Xenopus laevis
A2VD00
1424
168482
D907
W
R
R
G
A
D
P
D
E
R
K
Q
A
P
P
Zebra Danio
Brachydanio rerio
Q6PCR7
1267
151273
S903
R
K
R
G
E
G
E
S
E
W
R
R
P
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN25
1140
133861
E855
E
K
R
R
A
Q
Y
E
K
Q
R
A
K
E
E
Honey Bee
Apis mellifera
XP_397439
1143
134949
K861
R
E
A
E
R
L
A
K
I
E
K
Q
A
E
I
Nematode Worm
Caenorhab. elegans
P34339
1076
124390
L794
L
S
D
W
Q
A
K
L
E
A
V
R
N
N
R
Sea Urchin
Strong. purpuratus
XP_798957
1284
149812
D881
P
E
R
T
W
R
D
D
K
P
K
E
I
W
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XHR2
962
111545
K709
Q
K
R
L
E
E
E
K
I
L
H
E
Q
E
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD55
987
114281
L728
E
Q
Q
R
E
V
E
L
S
K
E
R
H
E
S
Baker's Yeast
Sacchar. cerevisiae
P38249
964
110326
N708
I
I
A
E
V
S
K
N
K
S
E
L
E
S
R
Red Bread Mold
Neurospora crassa
Q7RWT1
1007
114509
R755
K
R
R
R
D
A
E
R
E
M
E
K
Q
I
N
Conservation
Percent
Protein Identity:
100
99.9
86.5
94.2
N.A.
93.1
93.1
N.A.
88.2
75.6
72.1
75
N.A.
41.5
42.1
31.4
45.4
Protein Similarity:
100
99.9
87.4
95.9
N.A.
95.5
95.5
N.A.
93.1
81.7
81.4
82.1
N.A.
58
58.5
48.3
62.1
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
66.6
60
20
60
N.A.
13.3
6.6
20
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
80
73.3
40
66.6
N.A.
20
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
27.2
N.A.
27.1
23.3
28.2
Protein Similarity:
N.A.
43.8
N.A.
44.6
41
43.6
P-Site Identity:
N.A.
13.3
N.A.
13.3
0
13.3
P-Site Similarity:
N.A.
26.6
N.A.
26.6
20
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
6
12
39
6
6
0
6
0
6
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
6
6
39
12
0
0
0
0
0
0
0
% D
% Glu:
12
12
0
12
62
6
34
6
67
6
17
12
6
23
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
39
17
0
6
0
0
0
0
0
0
39
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
0
% H
% Ile:
6
6
0
0
0
0
0
0
12
0
0
0
6
6
6
% I
% Lys:
6
56
0
0
0
0
12
12
17
6
17
6
6
0
0
% K
% Leu:
6
0
0
6
0
6
0
12
0
6
0
6
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
6
0
0
0
0
6
6
6
% N
% Pro:
6
0
0
34
0
6
6
0
0
6
0
0
6
50
50
% P
% Gln:
6
6
6
0
6
6
0
0
0
6
0
12
12
0
6
% Q
% Arg:
56
17
34
17
6
6
0
6
0
6
56
62
0
0
17
% R
% Ser:
0
6
6
0
0
6
0
45
6
6
0
0
0
6
6
% S
% Thr:
0
0
0
6
0
6
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
6
12
0
0
0
0
6
0
0
6
6
% V
% Trp:
6
0
0
6
6
0
0
0
0
50
0
0
0
6
0
% W
% Tyr:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _