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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3A
All Species:
37.58
Human Site:
T1372
Identified Species:
48.63
UniProt:
Q14152
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.12
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14152
NP_003741.1
1382
166569
T1372
L
R
R
T
K
N
E
T
D
E
D
G
W
T
T
Chimpanzee
Pan troglodytes
XP_001153575
1382
166541
T1372
L
R
R
T
K
N
E
T
D
E
D
G
W
T
T
Rhesus Macaque
Macaca mulatta
XP_001102472
1228
147070
T1218
L
R
R
T
K
N
E
T
D
E
D
G
W
T
T
Dog
Lupus familis
XP_852131
1350
163016
T1340
L
R
R
T
K
N
E
T
D
E
D
G
W
T
T
Cat
Felis silvestris
Mouse
Mus musculus
P23116
1344
161918
T1334
L
R
R
T
K
N
E
T
D
E
D
G
W
T
T
Rat
Rattus norvegicus
Q1JU68
1354
163177
T1344
L
R
R
T
K
N
E
T
D
E
D
G
W
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514639
1362
163866
T1352
L
R
R
T
K
N
E
T
D
E
D
G
W
T
T
Chicken
Gallus gallus
XP_421787
1505
177889
T1495
A
R
R
T
K
N
E
T
D
E
E
G
W
T
T
Frog
Xenopus laevis
A2VD00
1424
168482
E1414
P
R
R
P
K
L
E
E
D
E
D
G
W
T
T
Zebra Danio
Brachydanio rerio
Q6PCR7
1267
151273
T1257
P
R
R
T
K
N
E
T
D
D
D
G
W
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN25
1140
133861
G1129
Q
E
K
E
N
K
A
G
D
D
G
E
W
T
S
Honey Bee
Apis mellifera
XP_397439
1143
134949
V1131
L
G
K
K
H
K
N
V
W
V
V
A
N
S
Y
Nematode Worm
Caenorhab. elegans
P34339
1076
124390
G1067
S
N
N
T
G
N
T
G
N
A
D
S
G
S
W
Sea Urchin
Strong. purpuratus
XP_798957
1284
149812
R1273
Q
Q
R
D
E
P
K
R
E
D
D
G
W
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XHR2
962
111545
S952
R
F
P
S
N
S
T
S
S
S
S
T
W
S
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD55
987
114281
R974
P
R
G
S
D
D
R
R
S
T
F
G
S
S
R
Baker's Yeast
Sacchar. cerevisiae
P38249
964
110326
R955
M
T
M
A
E
K
L
R
A
K
R
L
A
K
G
Red Bread Mold
Neurospora crassa
Q7RWT1
1007
114509
Y998
A
S
G
A
P
G
K
Y
V
P
K
W
R
R
E
Conservation
Percent
Protein Identity:
100
99.9
86.5
94.2
N.A.
93.1
93.1
N.A.
88.2
75.6
72.1
75
N.A.
41.5
42.1
31.4
45.4
Protein Similarity:
100
99.9
87.4
95.9
N.A.
95.5
95.5
N.A.
93.1
81.7
81.4
82.1
N.A.
58
58.5
48.3
62.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
73.3
86.6
N.A.
20
6.6
20
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
73.3
93.3
N.A.
40
20
33.3
73.3
Percent
Protein Identity:
N.A.
27.2
N.A.
27.1
23.3
28.2
Protein Similarity:
N.A.
43.8
N.A.
44.6
41
43.6
P-Site Identity:
N.A.
6.6
N.A.
13.3
0
0
P-Site Similarity:
N.A.
33.3
N.A.
33.3
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
12
0
0
6
0
6
6
0
6
6
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
6
6
0
0
62
17
62
0
0
0
0
% D
% Glu:
0
6
0
6
12
0
56
6
6
50
6
6
0
0
6
% E
% Phe:
0
6
0
0
0
0
0
0
0
0
6
0
0
0
0
% F
% Gly:
0
6
12
0
6
6
0
12
0
0
6
67
6
0
6
% G
% His:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
6
56
17
12
0
0
6
6
0
0
6
0
% K
% Leu:
45
0
0
0
0
6
6
0
0
0
0
6
0
0
0
% L
% Met:
6
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
6
0
12
56
6
0
6
0
0
0
6
0
0
% N
% Pro:
17
0
6
6
6
6
0
0
0
6
0
0
0
0
0
% P
% Gln:
12
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
6
62
62
0
0
0
6
17
0
0
6
0
6
6
12
% R
% Ser:
6
6
0
12
0
6
0
6
12
6
6
6
6
23
6
% S
% Thr:
0
6
0
56
0
0
12
50
0
6
0
6
0
67
62
% T
% Val:
0
0
0
0
0
0
0
6
6
6
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
6
0
0
6
73
0
6
% W
% Tyr:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _