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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3A
All Species:
31.52
Human Site:
T898
Identified Species:
40.78
UniProt:
Q14152
Number Species:
17
Phosphosite Substitution
Charge Score:
0.12
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14152
NP_003741.1
1382
166569
T898
G
D
R
D
S
E
G
T
W
R
K
G
P
E
A
Chimpanzee
Pan troglodytes
XP_001153575
1382
166541
T898
G
D
R
D
S
E
G
T
W
R
K
G
P
E
A
Rhesus Macaque
Macaca mulatta
XP_001102472
1228
147070
T734
G
D
R
D
S
E
G
T
W
R
K
G
P
E
A
Dog
Lupus familis
XP_852131
1350
163016
T898
G
D
R
D
S
E
G
T
W
R
K
G
P
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P23116
1344
161918
T898
G
D
R
D
S
E
G
T
W
R
K
G
P
E
A
Rat
Rattus norvegicus
Q1JU68
1354
163177
T898
G
D
R
D
S
E
G
T
W
R
K
G
P
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514639
1362
163866
T920
G
D
R
D
S
E
G
T
W
R
K
S
A
E
P
Chicken
Gallus gallus
XP_421787
1505
177889
S1030
D
R
G
E
S
E
S
S
W
R
R
G
G
E
T
Frog
Xenopus laevis
A2VD00
1424
168482
S898
R
W
G
D
R
E
E
S
G
W
R
R
G
A
D
Zebra Danio
Brachydanio rerio
Q6PCR7
1267
151273
G894
W
A
E
R
E
E
S
G
W
R
K
R
G
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN25
1140
133861
E846
R
R
L
E
R
E
A
E
D
E
K
R
R
A
Q
Honey Bee
Apis mellifera
XP_397439
1143
134949
E852
R
L
R
R
A
E
E
E
A
R
E
A
E
R
L
Nematode Worm
Caenorhab. elegans
P34339
1076
124390
K785
D
N
Q
E
T
L
E
K
K
L
S
D
W
Q
A
Sea Urchin
Strong. purpuratus
XP_798957
1284
149812
S872
R
M
K
D
T
R
P
S
E
P
E
R
T
W
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XHR2
962
111545
A700
E
A
P
L
I
E
Q
A
F
Q
K
R
L
E
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD55
987
114281
E719
V
E
E
R
E
F
Y
E
R
E
Q
Q
R
E
V
Baker's Yeast
Sacchar. cerevisiae
P38249
964
110326
Q699
L
D
L
D
T
I
K
Q
V
I
I
A
E
V
S
Red Bread Mold
Neurospora crassa
Q7RWT1
1007
114509
F746
H
E
R
R
R
D
E
F
E
K
R
R
R
D
A
Conservation
Percent
Protein Identity:
100
99.9
86.5
94.2
N.A.
93.1
93.1
N.A.
88.2
75.6
72.1
75
N.A.
41.5
42.1
31.4
45.4
Protein Similarity:
100
99.9
87.4
95.9
N.A.
95.5
95.5
N.A.
93.1
81.7
81.4
82.1
N.A.
58
58.5
48.3
62.1
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
80
40
13.3
33.3
N.A.
13.3
20
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
80
60
26.6
33.3
N.A.
20
33.3
40
33.3
Percent
Protein Identity:
N.A.
27.2
N.A.
27.1
23.3
28.2
Protein Similarity:
N.A.
43.8
N.A.
44.6
41
43.6
P-Site Identity:
N.A.
20
N.A.
6.6
13.3
13.3
P-Site Similarity:
N.A.
33.3
N.A.
20
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
6
0
6
6
6
0
0
12
6
12
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
45
0
56
0
6
0
0
6
0
0
6
0
6
6
% D
% Glu:
6
12
12
17
12
73
23
17
12
12
12
0
12
62
6
% E
% Phe:
0
0
0
0
0
6
0
6
6
0
0
0
0
0
0
% F
% Gly:
39
0
12
0
0
0
39
6
6
0
0
39
17
0
6
% G
% His:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
6
6
0
0
0
6
6
0
0
0
0
% I
% Lys:
0
0
6
0
0
0
6
6
6
6
56
0
0
0
0
% K
% Leu:
6
6
12
6
0
6
0
0
0
6
0
0
6
0
6
% L
% Met:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
6
0
0
0
6
0
0
6
0
0
34
0
6
% P
% Gln:
0
0
6
0
0
0
6
6
0
6
6
6
0
6
6
% Q
% Arg:
23
12
50
23
17
6
0
0
6
56
17
34
17
6
6
% R
% Ser:
0
0
0
0
45
0
12
17
0
0
6
6
0
0
6
% S
% Thr:
0
0
0
0
17
0
0
39
0
0
0
0
6
0
6
% T
% Val:
6
0
0
0
0
0
0
0
6
0
0
0
0
6
12
% V
% Trp:
6
6
0
0
0
0
0
0
50
6
0
0
6
6
0
% W
% Tyr:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _