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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3A
All Species:
44.77
Human Site:
Y4
Identified Species:
57.93
UniProt:
Q14152
Number Species:
17
Phosphosite Substitution
Charge Score:
0.12
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14152
NP_003741.1
1382
166569
Y4
_
_
_
_
M
P
A
Y
F
Q
R
P
E
N
A
Chimpanzee
Pan troglodytes
XP_001153575
1382
166541
Y4
_
_
_
_
M
P
A
Y
F
Q
R
P
E
N
A
Rhesus Macaque
Macaca mulatta
XP_001102472
1228
147070
E7
_
M
A
E
E
K
T
E
A
A
K
E
E
S
Q
Dog
Lupus familis
XP_852131
1350
163016
Y4
_
_
_
_
M
P
A
Y
F
Q
R
P
E
N
A
Cat
Felis silvestris
Mouse
Mus musculus
P23116
1344
161918
Y4
_
_
_
_
M
P
A
Y
F
Q
R
P
E
N
A
Rat
Rattus norvegicus
Q1JU68
1354
163177
Y4
_
_
_
_
M
P
A
Y
F
Q
R
P
E
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514639
1362
163866
L27
Q
N
L
A
T
P
K
L
Y
R
G
G
D
R
R
Chicken
Gallus gallus
XP_421787
1505
177889
Y4
_
_
_
_
M
P
V
Y
F
Q
R
P
E
N
A
Frog
Xenopus laevis
A2VD00
1424
168482
Y4
_
_
_
_
M
P
V
Y
F
Q
R
P
E
N
A
Zebra Danio
Brachydanio rerio
Q6PCR7
1267
151273
Y4
_
_
_
_
M
P
A
Y
F
Q
R
P
E
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN25
1140
133861
Y4
_
_
_
_
M
A
R
Y
T
Q
R
P
E
N
A
Honey Bee
Apis mellifera
XP_397439
1143
134949
Y4
_
_
_
_
M
A
R
Y
G
Q
R
P
E
N
A
Nematode Worm
Caenorhab. elegans
P34339
1076
124390
Y5
_
_
_
M
A
P
N
Y
F
Q
K
P
E
A
A
Sea Urchin
Strong. purpuratus
XP_798957
1284
149812
Y4
_
_
_
_
M
P
T
Y
F
Q
R
P
E
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XHR2
962
111545
F4
_
_
_
_
M
A
T
F
A
K
P
E
N
A
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD55
987
114281
F4
_
_
_
_
M
A
N
F
A
K
P
E
N
A
L
Baker's Yeast
Sacchar. cerevisiae
P38249
964
110326
P4
_
_
_
_
M
A
P
P
P
F
R
P
E
N
A
Red Bread Mold
Neurospora crassa
Q7RWT1
1007
114509
E10
L
L
V
E
L
S
V
E
Q
K
K
G
K
L
A
Conservation
Percent
Protein Identity:
100
99.9
86.5
94.2
N.A.
93.1
93.1
N.A.
88.2
75.6
72.1
75
N.A.
41.5
42.1
31.4
45.4
Protein Similarity:
100
99.9
87.4
95.9
N.A.
95.5
95.5
N.A.
93.1
81.7
81.4
82.1
N.A.
58
58.5
48.3
62.1
P-Site Identity:
100
100
7.1
100
N.A.
100
100
N.A.
6.6
90.9
90.9
100
N.A.
72.7
72.7
58.3
90.9
P-Site Similarity:
100
100
21.4
100
N.A.
100
100
N.A.
26.6
90.9
90.9
100
N.A.
72.7
72.7
66.6
90.9
Percent
Protein Identity:
N.A.
27.2
N.A.
27.1
23.3
28.2
Protein Similarity:
N.A.
43.8
N.A.
44.6
41
43.6
P-Site Identity:
N.A.
9
N.A.
9
54.5
6.6
P-Site Similarity:
N.A.
27.2
N.A.
27.2
54.5
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
6
6
28
34
0
17
6
0
0
0
17
78
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% D
% Glu:
0
0
0
12
6
0
0
12
0
0
0
17
78
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
56
6
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
6
0
6
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
6
6
0
0
17
17
0
6
0
0
% K
% Leu:
6
6
6
0
6
0
0
6
0
0
0
0
0
6
12
% L
% Met:
0
6
0
6
78
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
0
0
0
12
0
0
0
0
0
12
67
0
% N
% Pro:
0
0
0
0
0
62
6
6
6
0
12
73
0
0
0
% P
% Gln:
6
0
0
0
0
0
0
0
6
67
0
0
0
0
6
% Q
% Arg:
0
0
0
0
0
0
12
0
0
6
67
0
0
6
6
% R
% Ser:
0
0
0
0
0
6
0
0
0
0
0
0
0
6
0
% S
% Thr:
0
0
0
0
6
0
17
0
6
0
0
0
0
0
0
% T
% Val:
0
0
6
0
0
0
17
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
6
0
0
0
0
0
0
% Y
% Spaces:
89
84
84
78
0
0
0
0
0
0
0
0
0
0
0
% _