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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM53B
All Species:
12.73
Human Site:
S378
Identified Species:
31.11
UniProt:
Q14153
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14153
NP_055476.3
422
45768
S378
E
D
L
S
C
E
E
S
D
S
C
A
L
D
E
Chimpanzee
Pan troglodytes
XP_001135534
305
33427
V278
C
V
L
N
D
K
K
V
G
V
K
R
R
R
P
Rhesus Macaque
Macaca mulatta
XP_001083541
422
45669
S378
E
D
L
S
C
E
E
S
D
G
C
A
L
D
E
Dog
Lupus familis
XP_854058
461
50295
E415
C
K
E
E
Q
C
C
E
E
S
G
G
C
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGR5
422
45921
S378
E
D
L
S
C
D
E
S
D
G
C
S
L
D
E
Rat
Rattus norvegicus
NP_001101026
426
46490
S382
E
D
L
S
C
D
E
S
D
G
C
S
L
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509798
323
35914
V296
K
R
R
R
D
E
D
V
R
W
N
R
P
S
L
Chicken
Gallus gallus
Q5ZKN5
418
46229
A384
R
D
Y
K
K
A
A
A
V
C
E
S
D
E
D
Frog
Xenopus laevis
NP_001085276
413
45804
E385
P
P
L
S
E
S
E
E
D
T
S
D
C
E
S
Zebra Danio
Brachydanio rerio
NP_001007188
379
41139
C351
P
A
G
K
E
R
E
C
L
W
A
G
L
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72
97.3
79.3
N.A.
85.5
84.2
N.A.
30
36.4
34.8
41.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.2
98
82.8
N.A.
90.5
89.6
N.A.
44.7
53.7
49.7
54.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
6.6
N.A.
80
80
N.A.
6.6
6.6
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
93.3
13.3
N.A.
93.3
93.3
N.A.
20
33.3
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
10
10
0
0
10
20
0
10
0
% A
% Cys:
20
0
0
0
40
10
10
10
0
10
40
0
20
10
0
% C
% Asp:
0
50
0
0
20
20
10
0
50
0
0
10
10
40
10
% D
% Glu:
40
0
10
10
20
30
60
20
10
0
10
0
0
20
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
30
10
20
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
0
20
10
10
10
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
60
0
0
0
0
0
10
0
0
0
50
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
20
10
0
0
0
0
0
0
0
0
0
0
10
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
10
10
0
10
0
0
10
0
0
20
10
10
0
% R
% Ser:
0
0
0
50
0
10
0
40
0
20
10
30
0
10
20
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
20
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _