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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EFR3A All Species: 9.39
Human Site: S363 Identified Species: 20.67
UniProt: Q14156 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14156 NP_055952.2 821 92924 S363 L Q G G S V G S V N L N T S S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532333 871 98119 S413 L Q G G S V G S A S L N S S S
Cat Felis silvestris
Mouse Mus musculus Q8BG67 819 92594 V361 N D S Q K G S V G S V T V S S
Rat Rattus norvegicus NP_001124036 819 92505 V361 S D S Q K G S V G S V S L S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508880 1075 119852 S618 D A R S S V G S A S F S T S S
Chicken Gallus gallus XP_418436 820 92572 S363 D R R S S A G S A T F S T S S
Frog Xenopus laevis Q641A2 819 92526 A363 R R S S A G S A V F S S S S T
Zebra Danio Brachydanio rerio Q5SPP5 816 91941 C357 E L T G S Y D C T N I G T K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IGJ0 834 93943 Q392 T P E E S Q Y Q E A L I N A L
Honey Bee Apis mellifera XP_001120727 795 89930 V343 S L L S H L R V S V T R N Q S
Nematode Worm Caenorhab. elegans Q09263 859 96649 F364 H L R T S V D F E R S G K C S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 91.5 N.A. 97 97.5 N.A. 70.8 89.1 85.6 64.8 N.A. 37.5 43.3 36.2 N.A.
Protein Similarity: 100 N.A. N.A. 92.5 N.A. 98.6 99 N.A. 73.4 94.1 92.9 78.6 N.A. 56.9 64.1 55.4 N.A.
P-Site Identity: 100 N.A. N.A. 80 N.A. 13.3 13.3 N.A. 46.6 40 13.3 26.6 N.A. 13.3 6.6 20 N.A.
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 26.6 33.3 N.A. 60 53.3 53.3 33.3 N.A. 20 13.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 10 0 10 28 10 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % C
% Asp: 19 19 0 0 0 0 19 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 10 10 0 0 0 0 19 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 10 19 0 0 0 0 % F
% Gly: 0 0 19 28 0 28 37 0 19 0 0 19 0 0 0 % G
% His: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 10 % I
% Lys: 0 0 0 0 19 0 0 0 0 0 0 0 10 10 0 % K
% Leu: 19 28 10 0 0 10 0 0 0 0 28 0 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 19 0 19 19 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 19 0 19 0 10 0 10 0 0 0 0 0 10 0 % Q
% Arg: 10 19 28 0 0 0 10 0 0 10 0 10 0 0 0 % R
% Ser: 19 0 28 37 64 0 28 37 10 37 19 37 19 64 73 % S
% Thr: 10 0 10 10 0 0 0 0 10 10 10 10 37 0 10 % T
% Val: 0 0 0 0 0 37 0 28 19 10 19 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _