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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GIT2 All Species: 25.45
Human Site: Y525 Identified Species: 62.22
UniProt: Q14161 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14161 NP_001128685.1 759 84543 Y525 T G S G Q K P Y L P M G E A S
Chimpanzee Pan troglodytes XP_001139823 759 84603 Y525 T G S G Q K P Y L P M G E A S
Rhesus Macaque Macaca mulatta XP_001106038 759 84526 Y525 T G S G Q K P Y L P M G E A S
Dog Lupus familis XP_534715 759 84598 Y525 T G S G Q K P Y L P M G E V N
Cat Felis silvestris
Mouse Mus musculus Q9JLQ2 708 78777 P476 S G Q K P Y L P M G E A S H P
Rat Rattus norvegicus Q9Z272 770 85212 G530 S A L K P F G G A P G D E L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520619 1160 127477 Y926 T G S A P S P Y L P M G E A A
Chicken Gallus gallus NP_989537 757 84578 Y525 T G S G Q K P Y L P M G E V T
Frog Xenopus laevis NP_001085838 759 84716 Y525 T G S V Q K P Y L P I G E I T
Zebra Danio Brachydanio rerio NP_001119925 750 83330 S517 S S C S S S S S S S S A L K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 99.2 96.5 N.A. 86 65.1 N.A. 57.8 89.3 86.6 69.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.9 99.5 97.6 N.A. 89.5 76 N.A. 60.6 94.1 92.4 80.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 6.6 13.3 N.A. 73.3 86.6 73.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 20 26.6 N.A. 80 93.3 86.6 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 0 0 0 10 0 0 20 0 40 20 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 0 80 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 80 0 50 0 0 10 10 0 10 10 70 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % I
% Lys: 0 0 0 20 0 60 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 10 0 0 0 10 0 70 0 0 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 60 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 30 0 70 10 0 80 0 0 0 0 10 % P
% Gln: 0 0 10 0 60 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 30 10 70 10 10 20 10 10 10 10 10 0 10 0 30 % S
% Thr: 70 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 20 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 70 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _