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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLEC
All Species:
40.91
Human Site:
S135
Identified Species:
69.23
UniProt:
Q14165
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14165
NP_055545.1
292
32234
S135
A
E
V
Y
F
A
Q
S
Q
Q
K
V
F
D
V
Chimpanzee
Pan troglodytes
XP_522542
449
48823
S292
A
E
V
Y
F
A
Q
S
Q
Q
K
V
F
D
V
Rhesus Macaque
Macaca mulatta
XP_001090412
291
32120
S134
A
E
V
Y
F
A
Q
S
Q
Q
K
V
F
D
V
Dog
Lupus familis
XP_851391
289
32046
S132
A
E
V
Y
F
A
Q
S
Q
Q
K
V
F
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQI3
291
32324
S134
A
E
V
Y
F
A
Q
S
Q
Q
K
V
F
D
V
Rat
Rattus norvegicus
Q5FVQ4
291
32400
S134
A
E
V
Y
F
A
Q
S
Q
Q
K
V
F
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511781
282
31596
S125
A
E
V
Y
F
A
Q
S
Q
Q
K
V
F
D
V
Chicken
Gallus gallus
XP_415264
277
30546
S120
A
E
V
Y
F
A
Q
S
Q
Q
K
V
F
D
V
Frog
Xenopus laevis
Q6INX3
276
30669
S120
A
E
V
Y
F
A
Q
S
Q
Q
K
V
F
D
V
Zebra Danio
Brachydanio rerio
A9C3P0
285
31968
S124
A
E
V
Y
F
A
Q
S
Q
Q
K
V
F
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610087
347
39235
P147
C
E
V
Y
F
D
A
P
Q
K
K
V
F
D
V
Honey Bee
Apis mellifera
XP_001123304
193
22039
G58
D
P
L
M
N
K
V
G
T
A
S
D
Y
G
K
Nematode Worm
Caenorhab. elegans
NP_498951
304
33890
A128
S
E
V
Y
F
Q
K
A
G
E
K
I
F
N
I
Sea Urchin
Strong. purpuratus
XP_001188793
169
19156
M35
G
G
P
A
H
V
D
M
Y
G
T
H
Y
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65
98.9
97.2
N.A.
94.5
94.8
N.A.
75.3
84.5
81.1
74.3
N.A.
39.7
36.2
32.2
33.9
Protein Similarity:
100
65
99.3
98.2
N.A.
96.2
95.8
N.A.
80.4
91.4
87.3
83.5
N.A.
57
46.2
53.9
43.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
66.6
0
40
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
73.3
13.3
86.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
72
0
0
8
0
72
8
8
0
8
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
8
0
0
0
0
8
0
79
0
% D
% Glu:
0
86
0
0
0
0
0
0
0
8
0
0
0
0
8
% E
% Phe:
0
0
0
0
86
0
0
0
0
0
0
0
86
0
0
% F
% Gly:
8
8
0
0
0
0
0
8
8
8
0
0
0
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
8
8
0
0
8
86
0
0
0
8
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
8
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
72
0
79
72
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
72
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% T
% Val:
0
0
86
0
0
8
8
0
0
0
0
79
0
0
79
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
86
0
0
0
0
8
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _