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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLEC
All Species:
42.42
Human Site:
S179
Identified Species:
71.79
UniProt:
Q14165
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14165
NP_055545.1
292
32234
S179
S
I
R
K
G
K
L
S
V
Q
G
E
V
S
T
Chimpanzee
Pan troglodytes
XP_522542
449
48823
S336
S
I
R
K
G
K
L
S
V
Q
G
E
V
S
T
Rhesus Macaque
Macaca mulatta
XP_001090412
291
32120
S178
S
I
R
K
G
K
L
S
V
Q
G
E
V
S
T
Dog
Lupus familis
XP_851391
289
32046
S176
S
I
R
K
G
K
L
S
V
Q
G
E
V
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQI3
291
32324
S178
S
I
R
K
G
K
L
S
V
R
G
E
V
S
T
Rat
Rattus norvegicus
Q5FVQ4
291
32400
S178
S
I
R
K
G
K
L
S
V
Q
G
E
V
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511781
282
31596
S169
T
I
K
K
G
K
L
S
V
Q
G
E
V
S
T
Chicken
Gallus gallus
XP_415264
277
30546
S164
S
I
K
K
G
K
L
S
V
Q
G
E
V
S
T
Frog
Xenopus laevis
Q6INX3
276
30669
S164
S
I
K
K
G
K
L
S
V
Q
G
E
V
S
T
Zebra Danio
Brachydanio rerio
A9C3P0
285
31968
S168
S
I
K
R
G
K
L
S
V
H
G
E
V
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610087
347
39235
Y193
I
N
N
G
R
L
N
Y
E
G
E
V
S
D
V
Honey Bee
Apis mellifera
XP_001123304
193
22039
G91
R
Y
H
H
S
T
F
G
Y
D
I
P
I
N
E
Nematode Worm
Caenorhab. elegans
NP_498951
304
33890
S173
V
I
K
G
S
S
I
S
V
S
G
H
S
R
E
Sea Urchin
Strong. purpuratus
XP_001188793
169
19156
A67
A
R
V
P
P
S
D
A
I
L
Y
Q
T
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65
98.9
97.2
N.A.
94.5
94.8
N.A.
75.3
84.5
81.1
74.3
N.A.
39.7
36.2
32.2
33.9
Protein Similarity:
100
65
99.3
98.2
N.A.
96.2
95.8
N.A.
80.4
91.4
87.3
83.5
N.A.
57
46.2
53.9
43.8
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
86.6
93.3
93.3
80
N.A.
0
0
26.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
0
13.3
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
8
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
8
72
0
8
15
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
15
72
0
0
8
0
8
79
0
0
0
0
% G
% His:
0
0
8
8
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
8
79
0
0
0
0
8
0
8
0
8
0
8
0
0
% I
% Lys:
0
0
36
65
0
72
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
72
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
8
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
58
0
8
0
0
0
% Q
% Arg:
8
8
43
8
8
0
0
0
0
8
0
0
0
8
8
% R
% Ser:
65
0
0
0
15
15
0
79
0
8
0
0
15
72
0
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
0
0
8
0
72
% T
% Val:
8
0
8
0
0
0
0
0
79
0
0
8
72
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
8
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _