Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTLL12 All Species: 12.12
Human Site: S15 Identified Species: 19.05
UniProt: Q14166 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14166 NP_055955.1 644 74404 S15 E R R P A E R S S P G Q T P E
Chimpanzee Pan troglodytes XP_001171890 644 74373 S15 E R P P A E R S S P G Q T P E
Rhesus Macaque Macaca mulatta XP_001104848 751 85695 S122 R L R A E E R S N P G Q T P E
Dog Lupus familis XP_531703 642 73878 G8 M D A D A E P G A P G L T A E
Cat Felis silvestris
Mouse Mus musculus Q3UDE2 639 74025 G10 I Q S G P Q P G S P G R A E R
Rat Rattus norvegicus NP_001129394 639 73879 G10 G E P R S Q P G S P G R A E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518003 446 51715
Chicken Gallus gallus NP_001012558 627 72851 A22 L H G A A L R A S C V P A R Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956546 625 73192 T8 M Q N G S V N T E E E K E Y Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610325 626 72528 V11 I N K Y N E F V A L H K P Q L
Honey Bee Apis mellifera XP_394564 616 72647 N8 M D G I G L F N T F L Q S H R
Nematode Worm Caenorhab. elegans Q09512 662 76732 S11 D R S A Y P F S T F L D Q H S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002326123 868 98864 T62 R Q R R L L L T S A A S M P K
Maize Zea mays NP_001151803 872 99229 G11 A V A S A S S G D R I R T Y E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_177879 855 97525 A78 D V F L V D H A W T F R L P D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 83.8 87.2 N.A. 85.5 85 N.A. 50.7 75 N.A. 62.4 N.A. 40.3 46.2 32.1 N.A.
Protein Similarity: 100 99.3 85.3 92.6 N.A. 90.9 91.1 N.A. 58.7 85.7 N.A. 77.6 N.A. 59.1 63.8 49.5 N.A.
P-Site Identity: 100 93.3 66.6 40 N.A. 20 20 N.A. 0 20 N.A. 0 N.A. 6.6 6.6 13.3 N.A.
P-Site Similarity: 100 93.3 73.3 46.6 N.A. 40 40 N.A. 0 26.6 N.A. 33.3 N.A. 26.6 26.6 26.6 N.A.
Percent
Protein Identity: 28 28.1 N.A. 27.8 N.A. N.A.
Protein Similarity: 41.2 41.1 N.A. 42.8 N.A. N.A.
P-Site Identity: 20 20 N.A. 6.6 N.A. N.A.
P-Site Similarity: 40 26.6 N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 14 20 34 0 0 14 14 7 7 0 20 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 14 14 0 7 0 7 0 0 7 0 0 7 0 0 7 % D
% Glu: 14 7 0 0 7 34 0 0 7 7 7 0 7 14 34 % E
% Phe: 0 0 7 0 0 0 20 0 0 14 7 0 0 0 0 % F
% Gly: 7 0 14 14 7 0 0 27 0 0 40 0 0 0 0 % G
% His: 0 7 0 0 0 0 7 0 0 0 7 0 0 14 0 % H
% Ile: 14 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 7 0 0 0 0 0 0 0 0 14 0 0 7 % K
% Leu: 7 7 0 7 7 20 7 0 0 7 14 7 7 0 7 % L
% Met: 20 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 7 7 0 7 0 7 7 7 0 0 0 0 0 0 % N
% Pro: 0 0 14 14 7 7 20 0 0 40 0 7 7 34 0 % P
% Gln: 0 20 0 0 0 14 0 0 0 0 0 27 7 7 7 % Q
% Arg: 14 20 20 14 0 0 27 0 0 7 0 27 0 7 20 % R
% Ser: 0 0 14 7 14 7 7 27 40 0 0 7 7 0 7 % S
% Thr: 0 0 0 0 0 0 0 14 14 7 0 0 34 0 0 % T
% Val: 0 14 0 0 7 7 0 7 0 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 7 0 0 0 0 0 0 0 0 14 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _