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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL12
All Species:
17.88
Human Site:
S269
Identified Species:
28.1
UniProt:
Q14166
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14166
NP_055955.1
644
74404
S269
T
D
M
L
D
L
S
S
C
T
P
E
P
P
A
Chimpanzee
Pan troglodytes
XP_001171890
644
74373
S269
T
D
M
L
D
L
S
S
C
T
P
E
P
P
A
Rhesus Macaque
Macaca mulatta
XP_001104848
751
85695
S376
T
D
M
L
D
L
S
S
C
T
P
E
P
P
A
Dog
Lupus familis
XP_531703
642
73878
S267
A
D
M
L
D
F
S
S
S
T
P
E
P
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3UDE2
639
74025
F264
A
D
M
L
D
L
S
F
S
T
P
E
P
P
A
Rat
Rattus norvegicus
NP_001129394
639
73879
S264
A
D
M
L
D
L
S
S
S
T
P
E
P
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518003
446
51715
E134
L
N
Q
G
S
A
E
E
Q
V
P
V
W
Y
V
Chicken
Gallus gallus
NP_001012558
627
72851
C252
N
E
V
L
D
V
N
C
F
T
P
E
P
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956546
625
73192
D250
E
E
L
D
A
V
S
D
D
V
Q
E
P
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610325
626
72528
S240
D
A
D
L
T
G
E
S
F
L
Q
V
E
P
R
Honey Bee
Apis mellifera
XP_394564
616
72647
S233
E
T
S
F
L
G
E
S
F
A
Q
V
E
P
D
Nematode Worm
Caenorhab. elegans
Q09512
662
76732
K282
W
A
A
Q
D
F
S
K
E
T
M
I
P
D
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326123
868
98864
Q497
T
A
Y
F
H
T
P
Q
Y
Y
F
I
Q
E
Y
Maize
Zea mays
NP_001151803
872
99229
E497
T
A
W
F
R
T
P
E
N
Y
F
I
Q
E
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177879
855
97525
E485
T
A
W
F
Q
T
P
E
N
Y
F
I
H
E
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
83.8
87.2
N.A.
85.5
85
N.A.
50.7
75
N.A.
62.4
N.A.
40.3
46.2
32.1
N.A.
Protein Similarity:
100
99.3
85.3
92.6
N.A.
90.9
91.1
N.A.
58.7
85.7
N.A.
77.6
N.A.
59.1
63.8
49.5
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
80
86.6
N.A.
6.6
40
N.A.
20
N.A.
20
13.3
33.3
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
80
86.6
N.A.
13.3
66.6
N.A.
40
N.A.
20
13.3
33.3
N.A.
Percent
Protein Identity:
28
28.1
N.A.
27.8
N.A.
N.A.
Protein Similarity:
41.2
41.1
N.A.
42.8
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
6.6
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
34
7
0
7
7
0
0
0
7
0
0
0
0
40
% A
% Cys:
0
0
0
0
0
0
0
7
20
0
0
0
0
0
0
% C
% Asp:
7
40
7
7
54
0
0
7
7
0
0
0
0
7
27
% D
% Glu:
14
14
0
0
0
0
20
20
7
0
0
54
14
20
0
% E
% Phe:
0
0
0
27
0
14
0
7
20
0
20
0
0
0
14
% F
% Gly:
0
0
0
7
0
14
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
27
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
7
0
7
54
7
34
0
0
0
7
0
0
0
0
0
% L
% Met:
0
0
40
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
7
0
14
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
20
0
0
0
54
0
60
54
0
% P
% Gln:
0
0
7
7
7
0
0
7
7
0
20
0
14
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
0
7
0
7
0
54
47
20
0
0
0
0
14
0
% S
% Thr:
40
7
0
0
7
20
0
0
0
54
0
0
0
0
0
% T
% Val:
0
0
7
0
0
14
0
0
0
14
0
20
0
0
7
% V
% Trp:
7
0
14
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
7
20
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _