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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL12
All Species:
21.21
Human Site:
S434
Identified Species:
33.33
UniProt:
Q14166
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14166
NP_055955.1
644
74404
S434
L
D
T
H
V
T
K
S
L
H
S
I
I
R
H
Chimpanzee
Pan troglodytes
XP_001171890
644
74373
S434
L
D
T
H
V
T
K
S
L
H
S
I
I
R
H
Rhesus Macaque
Macaca mulatta
XP_001104848
751
85695
S541
L
D
T
H
V
T
K
S
L
H
S
I
I
R
H
Dog
Lupus familis
XP_531703
642
73878
S432
L
D
T
H
I
T
R
S
L
H
S
I
I
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3UDE2
639
74025
N429
L
D
T
H
V
T
N
N
L
H
S
I
I
R
H
Rat
Rattus norvegicus
NP_001129394
639
73879
N429
L
D
T
H
V
T
N
N
L
H
S
I
I
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518003
446
51715
Q272
N
L
T
H
P
R
F
Q
L
T
S
S
K
A
E
Chicken
Gallus gallus
NP_001012558
627
72851
S417
L
D
T
H
I
T
N
S
L
N
N
I
I
R
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956546
625
73192
S415
L
D
T
H
I
T
D
S
L
D
Y
I
I
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610325
626
72528
N414
L
D
T
H
I
T
D
N
I
K
Q
I
V
R
L
Honey Bee
Apis mellifera
XP_394564
616
72647
N408
L
D
T
H
I
T
K
N
L
F
H
I
L
R
L
Nematode Worm
Caenorhab. elegans
Q09512
662
76732
D456
M
D
M
T
V
T
E
D
L
N
Q
I
I
R
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326123
868
98864
N665
I
D
T
T
V
T
D
N
L
S
A
I
I
R
L
Maize
Zea mays
NP_001151803
872
99229
D669
I
D
T
T
V
T
G
D
L
S
A
I
I
R
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177879
855
97525
N653
I
D
T
S
I
T
D
N
L
S
A
I
I
R
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
83.8
87.2
N.A.
85.5
85
N.A.
50.7
75
N.A.
62.4
N.A.
40.3
46.2
32.1
N.A.
Protein Similarity:
100
99.3
85.3
92.6
N.A.
90.9
91.1
N.A.
58.7
85.7
N.A.
77.6
N.A.
59.1
63.8
49.5
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
26.6
73.3
N.A.
66.6
N.A.
46.6
60
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
93.3
N.A.
73.3
N.A.
73.3
80
66.6
N.A.
Percent
Protein Identity:
28
28.1
N.A.
27.8
N.A.
N.A.
Protein Similarity:
41.2
41.1
N.A.
42.8
N.A.
N.A.
P-Site Identity:
53.3
53.3
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
73.3
66.6
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
20
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
94
0
0
0
0
27
14
0
7
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
74
0
0
0
0
0
40
7
0
0
0
47
% H
% Ile:
20
0
0
0
40
0
0
0
7
0
0
94
80
0
0
% I
% Lys:
0
0
0
0
0
0
27
0
0
7
0
0
7
0
0
% K
% Leu:
67
7
0
0
0
0
0
0
94
0
0
0
7
0
27
% L
% Met:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
14
% M
% Asn:
7
0
0
0
0
0
20
40
0
14
7
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
14
0
0
0
7
% Q
% Arg:
0
0
0
0
0
7
7
0
0
0
0
0
0
94
0
% R
% Ser:
0
0
0
7
0
0
0
40
0
20
47
7
0
0
0
% S
% Thr:
0
0
94
20
0
94
0
0
0
7
0
0
0
0
0
% T
% Val:
0
0
0
0
54
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _