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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL12
All Species:
47.88
Human Site:
S444
Identified Species:
75.24
UniProt:
Q14166
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14166
NP_055955.1
644
74404
S444
S
I
I
R
H
R
E
S
T
P
K
V
V
S
K
Chimpanzee
Pan troglodytes
XP_001171890
644
74373
S444
S
I
I
R
H
R
E
S
T
P
K
V
V
S
K
Rhesus Macaque
Macaca mulatta
XP_001104848
751
85695
S551
S
I
I
R
H
R
E
S
T
P
K
V
V
S
K
Dog
Lupus familis
XP_531703
642
73878
S442
S
I
I
R
H
R
E
S
T
P
K
V
V
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3UDE2
639
74025
S439
S
I
I
R
H
R
E
S
T
P
K
V
V
S
K
Rat
Rattus norvegicus
NP_001129394
639
73879
S439
S
I
I
R
H
R
E
S
T
P
K
V
V
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518003
446
51715
I282
S
S
K
A
E
A
D
I
L
Y
T
F
S
H
F
Chicken
Gallus gallus
NP_001012558
627
72851
S427
N
I
I
R
H
R
E
S
S
P
K
V
V
C
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956546
625
73192
S425
Y
I
I
R
Q
R
E
S
T
P
K
V
V
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610325
626
72528
T424
Q
I
V
R
L
P
A
T
G
P
K
I
A
Q
K
Honey Bee
Apis mellifera
XP_394564
616
72647
T418
H
I
L
R
L
P
S
T
G
P
K
I
A
Q
K
Nematode Worm
Caenorhab. elegans
Q09512
662
76732
T466
Q
I
I
R
M
I
E
T
G
P
K
I
V
C
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326123
868
98864
T675
A
I
I
R
L
M
E
T
G
P
K
I
C
Q
K
Maize
Zea mays
NP_001151803
872
99229
T679
A
I
I
R
L
M
E
T
G
P
K
I
C
Q
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177879
855
97525
T663
A
I
I
R
M
M
E
T
G
P
K
I
C
Q
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
83.8
87.2
N.A.
85.5
85
N.A.
50.7
75
N.A.
62.4
N.A.
40.3
46.2
32.1
N.A.
Protein Similarity:
100
99.3
85.3
92.6
N.A.
90.9
91.1
N.A.
58.7
85.7
N.A.
77.6
N.A.
59.1
63.8
49.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
80
N.A.
86.6
N.A.
33.3
33.3
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
93.3
N.A.
86.6
N.A.
53.3
53.3
66.6
N.A.
Percent
Protein Identity:
28
28.1
N.A.
27.8
N.A.
N.A.
Protein Similarity:
41.2
41.1
N.A.
42.8
N.A.
N.A.
P-Site Identity:
46.6
46.6
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
66.6
66.6
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
7
0
7
7
0
0
0
0
0
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
20
14
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
7
0
80
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% F
% Gly:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% G
% His:
7
0
0
0
47
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
94
80
0
0
7
0
7
0
0
0
40
0
0
0
% I
% Lys:
0
0
7
0
0
0
0
0
0
0
94
0
0
0
87
% K
% Leu:
0
0
7
0
27
0
0
0
7
0
0
0
0
0
0
% L
% Met:
0
0
0
0
14
20
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
14
0
0
0
94
0
0
0
0
0
% P
% Gln:
14
0
0
0
7
0
0
0
0
0
0
0
0
34
0
% Q
% Arg:
0
0
0
94
0
54
0
0
0
0
0
0
0
0
0
% R
% Ser:
47
7
0
0
0
0
7
54
7
0
0
0
7
47
0
% S
% Thr:
0
0
0
0
0
0
0
40
47
0
7
0
0
0
0
% T
% Val:
0
0
7
0
0
0
0
0
0
0
0
54
60
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _