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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL12
All Species:
26.97
Human Site:
S450
Identified Species:
42.38
UniProt:
Q14166
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14166
NP_055955.1
644
74404
S450
E
S
T
P
K
V
V
S
K
Y
I
E
S
P
V
Chimpanzee
Pan troglodytes
XP_001171890
644
74373
S450
E
S
T
P
K
V
V
S
K
Y
I
E
S
P
V
Rhesus Macaque
Macaca mulatta
XP_001104848
751
85695
S557
E
S
T
P
K
V
V
S
K
Y
I
E
S
P
V
Dog
Lupus familis
XP_531703
642
73878
S448
E
S
T
P
K
V
V
S
K
Y
I
E
S
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3UDE2
639
74025
S445
E
S
T
P
K
V
V
S
K
Y
I
E
S
P
V
Rat
Rattus norvegicus
NP_001129394
639
73879
S445
E
S
T
P
K
V
V
S
K
Y
I
E
S
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518003
446
51715
H288
D
I
L
Y
T
F
S
H
F
K
D
Y
R
A
L
Chicken
Gallus gallus
NP_001012558
627
72851
C433
E
S
S
P
K
V
V
C
K
Y
I
E
N
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956546
625
73192
S431
E
S
T
P
K
V
V
S
K
Y
L
E
D
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610325
626
72528
Q430
A
T
G
P
K
I
A
Q
K
Y
I
E
R
P
V
Honey Bee
Apis mellifera
XP_394564
616
72647
Q424
S
T
G
P
K
I
A
Q
K
Y
I
T
N
P
V
Nematode Worm
Caenorhab. elegans
Q09512
662
76732
C472
E
T
G
P
K
I
V
C
E
Y
I
P
R
P
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326123
868
98864
Q681
E
T
G
P
K
I
C
Q
K
Y
I
E
H
P
A
Maize
Zea mays
NP_001151803
872
99229
Q685
E
T
G
P
K
I
C
Q
K
Y
I
E
R
P
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177879
855
97525
Q669
E
T
G
P
K
I
C
Q
K
Y
I
E
H
P
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
83.8
87.2
N.A.
85.5
85
N.A.
50.7
75
N.A.
62.4
N.A.
40.3
46.2
32.1
N.A.
Protein Similarity:
100
99.3
85.3
92.6
N.A.
90.9
91.1
N.A.
58.7
85.7
N.A.
77.6
N.A.
59.1
63.8
49.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
80
N.A.
86.6
N.A.
53.3
46.6
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
93.3
N.A.
93.3
N.A.
66.6
66.6
73.3
N.A.
Percent
Protein Identity:
28
28.1
N.A.
27.8
N.A.
N.A.
Protein Similarity:
41.2
41.1
N.A.
42.8
N.A.
N.A.
P-Site Identity:
53.3
53.3
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
66.6
66.6
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
14
0
0
0
0
0
0
7
20
% A
% Cys:
0
0
0
0
0
0
20
14
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% D
% Glu:
80
0
0
0
0
0
0
0
7
0
0
80
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
14
0
0
% H
% Ile:
0
7
0
0
0
40
0
0
0
0
87
0
0
0
0
% I
% Lys:
0
0
0
0
94
0
0
0
87
7
0
0
0
0
0
% K
% Leu:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% N
% Pro:
0
0
0
94
0
0
0
0
0
0
0
7
0
94
0
% P
% Gln:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
27
0
0
% R
% Ser:
7
54
7
0
0
0
7
47
0
0
0
0
40
0
0
% S
% Thr:
0
40
47
0
7
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
0
0
0
54
60
0
0
0
0
0
0
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
94
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _