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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL12
All Species:
36.06
Human Site:
Y344
Identified Species:
56.67
UniProt:
Q14166
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14166
NP_055955.1
644
74404
Y344
N
F
S
H
F
K
D
Y
R
K
L
S
Q
E
R
Chimpanzee
Pan troglodytes
XP_001171890
644
74373
Y344
N
F
S
H
F
K
D
Y
R
K
L
S
Q
E
R
Rhesus Macaque
Macaca mulatta
XP_001104848
751
85695
Y451
N
F
S
H
F
K
D
Y
R
K
L
S
Q
E
R
Dog
Lupus familis
XP_531703
642
73878
Y342
N
F
S
H
F
K
D
Y
R
R
L
S
Q
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UDE2
639
74025
Y339
H
F
S
H
F
K
D
Y
M
K
L
S
Q
E
S
Rat
Rattus norvegicus
NP_001129394
639
73879
Y339
H
F
S
H
F
K
D
Y
T
K
L
S
Q
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518003
446
51715
R195
R
D
F
A
Y
G
E
R
D
R
L
I
R
K
C
Chicken
Gallus gallus
NP_001012558
627
72851
Y327
N
F
S
H
F
K
D
Y
R
K
L
S
E
E
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956546
625
73192
Y325
A
F
S
H
I
R
E
Y
R
K
L
S
E
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610325
626
72528
F316
L
T
H
H
F
K
N
F
E
D
F
A
D
R
S
Honey Bee
Apis mellifera
XP_394564
616
72647
Y309
Y
T
S
H
F
K
E
Y
K
E
L
S
I
R
S
Nematode Worm
Caenorhab. elegans
Q09512
662
76732
Y368
M
I
K
H
F
H
D
Y
K
Q
L
S
E
E
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326123
868
98864
D576
T
G
M
Q
V
D
D
D
V
K
R
A
A
G
I
Maize
Zea mays
NP_001151803
872
99229
E580
V
S
M
Q
V
D
S
E
V
K
N
A
V
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177879
855
97525
E564
T
S
V
Q
V
D
D
E
L
K
K
E
V
G
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
83.8
87.2
N.A.
85.5
85
N.A.
50.7
75
N.A.
62.4
N.A.
40.3
46.2
32.1
N.A.
Protein Similarity:
100
99.3
85.3
92.6
N.A.
90.9
91.1
N.A.
58.7
85.7
N.A.
77.6
N.A.
59.1
63.8
49.5
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
6.6
93.3
N.A.
66.6
N.A.
20
46.6
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
40
100
N.A.
86.6
N.A.
40
66.6
66.6
N.A.
Percent
Protein Identity:
28
28.1
N.A.
27.8
N.A.
N.A.
Protein Similarity:
41.2
41.1
N.A.
42.8
N.A.
N.A.
P-Site Identity:
13.3
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
0
0
0
0
20
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
7
0
0
0
20
67
7
7
7
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
0
20
14
7
7
0
7
20
60
0
% E
% Phe:
0
54
7
0
67
0
0
7
0
0
7
0
0
0
0
% F
% Gly:
0
7
0
0
0
7
0
0
0
0
0
0
0
20
0
% G
% His:
14
0
7
74
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
0
0
0
0
0
0
7
7
0
14
% I
% Lys:
0
0
7
0
0
60
0
0
14
67
7
0
0
7
0
% K
% Leu:
7
0
0
0
0
0
0
0
7
0
74
0
0
0
7
% L
% Met:
7
0
14
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
34
0
0
0
0
0
7
0
0
0
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
20
0
0
0
0
0
7
0
0
40
0
0
% Q
% Arg:
7
0
0
0
0
7
0
7
40
14
7
0
7
14
40
% R
% Ser:
0
14
60
0
0
0
7
0
0
0
0
67
0
0
27
% S
% Thr:
14
14
0
0
0
0
0
0
7
0
0
0
0
0
0
% T
% Val:
7
0
7
0
20
0
0
0
14
0
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
7
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _