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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL12
All Species:
16.06
Human Site:
Y48
Identified Species:
25.24
UniProt:
Q14166
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14166
NP_055955.1
644
74404
Y48
A
S
G
V
P
E
R
Y
W
G
R
L
L
H
K
Chimpanzee
Pan troglodytes
XP_001171890
644
74373
Y48
A
S
G
V
P
E
R
Y
W
G
R
L
L
H
K
Rhesus Macaque
Macaca mulatta
XP_001104848
751
85695
Y155
A
S
G
V
P
E
R
Y
W
G
R
L
L
H
K
Dog
Lupus familis
XP_531703
642
73878
Y41
A
S
G
V
P
E
R
Y
W
G
R
L
L
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3UDE2
639
74025
L43
A
S
G
V
P
E
R
L
W
G
R
L
L
H
K
Rat
Rattus norvegicus
NP_001129394
639
73879
L43
A
S
G
V
P
E
R
L
W
G
S
L
L
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518003
446
51715
Chicken
Gallus gallus
NP_001012558
627
72851
E60
V
E
E
V
D
E
E
E
E
G
D
E
A
M
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956546
625
73192
Y34
A
A
R
I
P
P
L
Y
W
K
S
L
H
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610325
626
72528
F40
R
K
L
T
T
E
T
F
D
A
G
E
A
L
Q
Honey Bee
Apis mellifera
XP_394564
616
72647
L35
W
Q
V
L
F
K
K
L
Q
C
Q
T
F
D
S
Nematode Worm
Caenorhab. elegans
Q09512
662
76732
L38
W
H
S
L
Y
K
K
L
S
D
Q
T
F
D
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326123
868
98864
I118
S
N
S
D
V
E
E
I
D
G
D
G
V
S
R
Maize
Zea mays
NP_001151803
872
99229
L37
A
A
G
I
P
P
S
L
H
Q
R
L
Y
R
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177879
855
97525
F165
S
L
H
L
P
S
K
F
Q
D
L
V
A
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
83.8
87.2
N.A.
85.5
85
N.A.
50.7
75
N.A.
62.4
N.A.
40.3
46.2
32.1
N.A.
Protein Similarity:
100
99.3
85.3
92.6
N.A.
90.9
91.1
N.A.
58.7
85.7
N.A.
77.6
N.A.
59.1
63.8
49.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
0
20
N.A.
40
N.A.
6.6
0
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
0
26.6
N.A.
53.3
N.A.
20
26.6
26.6
N.A.
Percent
Protein Identity:
28
28.1
N.A.
27.8
N.A.
N.A.
Protein Similarity:
41.2
41.1
N.A.
42.8
N.A.
N.A.
P-Site Identity:
13.3
40
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
40
53.3
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
14
0
0
0
0
0
0
0
7
0
0
20
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
7
7
0
0
0
14
14
14
0
0
14
0
% D
% Glu:
0
7
7
0
0
60
14
7
7
0
0
14
0
0
7
% E
% Phe:
0
0
0
0
7
0
0
14
0
0
0
0
14
0
0
% F
% Gly:
0
0
47
0
0
0
0
0
0
54
7
7
0
0
0
% G
% His:
0
7
7
0
0
0
0
0
7
0
0
0
7
40
0
% H
% Ile:
0
0
0
14
0
0
0
7
0
0
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
14
20
0
0
7
0
0
0
0
54
% K
% Leu:
0
7
7
20
0
0
7
34
0
0
7
54
40
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
60
14
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
14
7
14
0
0
0
7
% Q
% Arg:
7
0
7
0
0
0
40
0
0
0
40
0
0
7
7
% R
% Ser:
14
40
14
0
0
7
7
0
7
0
14
0
0
7
14
% S
% Thr:
0
0
0
7
7
0
7
0
0
0
0
14
0
0
0
% T
% Val:
7
0
7
47
7
0
0
0
0
0
0
7
7
0
0
% V
% Trp:
14
0
0
0
0
0
0
0
47
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
34
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _