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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPP2 All Species: 13.33
Human Site: S21 Identified Species: 20.95
UniProt: Q14168 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14168 NP_005365.3 576 64581 S21 Q V L D N L G S L P S A T G A
Chimpanzee Pan troglodytes XP_511538 656 72549 V35 A L G T S V E V L E G E E E K
Rhesus Macaque Macaca mulatta XP_001096776 582 65885 E30 I F L K G I M E N P I V K S L
Dog Lupus familis XP_548068 552 61535 S21 Q V L D N L G S L P N A T G A
Cat Felis silvestris
Mouse Mus musculus Q9WV34 552 61537 S21 Q V L D N L G S L P N A T G A
Rat Rattus norvegicus Q62915 909 103240 I74 H M L K H P H I V E L L E T Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507958 540 61012 D21 S T G A E E I D L I F L K G I
Chicken Gallus gallus Q5ZJ00 468 52501
Frog Xenopus laevis NP_001087762 532 59489 G24 L D L I F L K G I M E S P Q A
Zebra Danio Brachydanio rerio Q6P0D7 576 65174 S23 E L L S V L P S Q L Q P H V E
Tiger Blowfish Takifugu rubipres P49697 467 52590
Fruit Fly Dros. melanogaster Q24210 898 100893 T49 I V D V A K F T A S P G L S T
Honey Bee Apis mellifera XP_391909 602 67965 T56 V M E K C L V T V P A A F M H
Nematode Worm Caenorhab. elegans P54936 961 108794 R54 S I N L N L F R Q H T G L G F
Sea Urchin Strong. purpuratus XP_791632 556 63023 M24 A M V D S L D M L G N S T H A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.5 66.3 93.4 N.A. 93.4 30.2 N.A. 66.1 36.2 72 36.8 33.5 31.9 42.3 26.9 46
Protein Similarity: 100 82.9 81.7 94.7 N.A. 94.9 43.5 N.A. 80.5 53.1 82.1 55 51.3 43.7 61.9 41.7 65.8
P-Site Identity: 100 6.6 13.3 93.3 N.A. 93.3 6.6 N.A. 13.3 0 20 20 0 6.6 20 20 33.3
P-Site Similarity: 100 26.6 20 100 N.A. 100 26.6 N.A. 13.3 0 33.3 33.3 0 13.3 46.6 33.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 7 7 0 0 0 7 0 7 27 0 0 34 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 27 0 0 7 7 0 0 0 0 0 0 0 % D
% Glu: 7 0 7 0 7 7 7 7 0 14 7 7 14 7 7 % E
% Phe: 0 7 0 0 7 0 14 0 0 0 7 0 7 0 7 % F
% Gly: 0 0 14 0 7 0 20 7 0 7 7 14 0 34 0 % G
% His: 7 0 0 0 7 0 7 0 0 7 0 0 7 7 7 % H
% Ile: 14 7 0 7 0 7 7 7 7 7 7 0 0 0 7 % I
% Lys: 0 0 0 20 0 7 7 0 0 0 0 0 14 0 7 % K
% Leu: 7 14 47 7 0 54 0 0 40 7 7 14 14 0 7 % L
% Met: 0 20 0 0 0 0 7 7 0 7 0 0 0 7 0 % M
% Asn: 0 0 7 0 27 0 0 0 7 0 20 0 0 0 0 % N
% Pro: 0 0 0 0 0 7 7 0 0 34 7 7 7 0 0 % P
% Gln: 20 0 0 0 0 0 0 0 14 0 7 0 0 7 0 % Q
% Arg: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % R
% Ser: 14 0 0 7 14 0 0 27 0 7 7 14 0 14 0 % S
% Thr: 0 7 0 7 0 0 0 14 0 0 7 0 27 7 7 % T
% Val: 7 27 7 7 7 7 7 7 14 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _