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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP2
All Species:
35.45
Human Site:
S410
Identified Species:
55.71
UniProt:
Q14168
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14168
NP_005365.3
576
64581
S410
G
T
T
V
P
Y
T
S
R
R
P
K
D
S
E
Chimpanzee
Pan troglodytes
XP_511538
656
72549
S490
G
T
T
V
P
Y
T
S
R
R
P
K
D
S
E
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
S416
G
T
T
V
P
F
T
S
R
K
P
R
E
D
E
Dog
Lupus familis
XP_548068
552
61535
S386
G
T
T
V
P
Y
T
S
R
R
P
K
D
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV34
552
61537
S386
G
T
T
V
P
Y
T
S
R
R
P
K
D
S
E
Rat
Rattus norvegicus
Q62915
909
103240
I743
R
H
I
K
N
T
L
I
T
K
H
P
E
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
S374
G
T
T
V
P
F
T
S
R
K
P
R
E
D
E
Chicken
Gallus gallus
Q5ZJ00
468
52501
M313
S
N
N
P
E
K
F
M
Y
P
P
P
Y
T
T
Frog
Xenopus laevis
NP_001087762
532
59489
S366
G
T
T
I
P
Y
T
S
R
K
R
K
E
G
E
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
S404
S
V
T
I
P
H
T
S
R
S
K
R
H
Q
E
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
S312
T
K
Y
P
E
K
F
S
Y
P
V
P
H
T
T
Fruit Fly
Dros. melanogaster
Q24210
898
100893
P742
Y
P
D
K
Y
A
Y
P
I
P
H
T
T
R
P
Honey Bee
Apis mellifera
XP_391909
602
67965
S435
G
T
I
V
P
Y
T
S
R
P
P
R
V
L
E
Nematode Worm
Caenorhab. elegans
P54936
961
108794
I795
R
H
I
K
N
T
L
I
H
R
H
P
N
R
F
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
T390
D
V
P
I
A
H
T
T
R
L
P
R
E
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
66.3
93.4
N.A.
93.4
30.2
N.A.
66.1
36.2
72
36.8
33.5
31.9
42.3
26.9
46
Protein Similarity:
100
82.9
81.7
94.7
N.A.
94.9
43.5
N.A.
80.5
53.1
82.1
55
51.3
43.7
61.9
41.7
65.8
P-Site Identity:
100
100
66.6
100
N.A.
100
0
N.A.
66.6
6.6
66.6
40
6.6
0
66.6
6.6
26.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
13.3
N.A.
93.3
13.3
86.6
60
13.3
0
73.3
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
0
0
0
0
0
0
0
27
14
0
% D
% Glu:
0
0
0
0
14
0
0
0
0
0
0
0
34
0
67
% E
% Phe:
0
0
0
0
0
14
14
0
0
0
0
0
0
0
14
% F
% Gly:
54
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% G
% His:
0
14
0
0
0
14
0
0
7
0
20
0
14
0
0
% H
% Ile:
0
0
20
20
0
0
0
14
7
0
0
0
0
0
0
% I
% Lys:
0
7
0
20
0
14
0
0
0
27
7
34
0
0
0
% K
% Leu:
0
0
0
0
0
0
14
0
0
7
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
14
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
7
7
14
60
0
0
7
0
27
60
27
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
14
0
0
0
0
0
0
0
67
34
7
34
0
20
0
% R
% Ser:
14
0
0
0
0
0
0
67
0
7
0
0
0
27
0
% S
% Thr:
7
54
54
0
0
14
67
7
7
0
0
7
7
14
14
% T
% Val:
0
14
0
47
0
0
0
0
0
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
7
40
7
0
14
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _