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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP2
All Species:
18.79
Human Site:
S424
Identified Species:
29.52
UniProt:
Q14168
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14168
NP_005365.3
576
64581
S424
E
R
E
G
Q
G
Y
S
F
V
S
R
G
E
M
Chimpanzee
Pan troglodytes
XP_511538
656
72549
S504
E
R
E
G
Q
G
Y
S
F
V
S
R
G
E
M
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
K430
E
K
D
G
Q
A
Y
K
F
V
S
R
S
E
M
Dog
Lupus familis
XP_548068
552
61535
S400
E
R
E
G
Q
G
Y
S
F
V
S
R
S
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV34
552
61537
S400
E
R
E
G
Q
G
Y
S
F
V
S
R
G
E
M
Rat
Rattus norvegicus
Q62915
909
103240
T757
F
A
Y
P
I
P
H
T
T
R
P
P
K
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
K388
E
K
D
G
Q
A
Y
K
F
V
S
R
A
E
M
Chicken
Gallus gallus
Q5ZJ00
468
52501
E327
T
R
P
Q
K
K
N
E
V
D
G
K
D
Y
Y
Frog
Xenopus laevis
NP_001087762
532
59489
S380
E
W
D
G
Q
S
Y
S
F
V
T
R
A
E
M
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
H418
E
S
E
G
V
E
Y
H
F
I
S
K
N
L
F
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
D326
T
R
P
Q
R
K
G
D
A
N
G
E
E
Y
F
Fruit Fly
Dros. melanogaster
Q24210
898
100893
N756
P
A
K
P
E
E
E
N
G
R
S
Y
Y
F
V
Honey Bee
Apis mellifera
XP_391909
602
67965
W449
E
E
D
G
K
S
Y
W
F
I
D
R
E
S
M
Nematode Worm
Caenorhab. elegans
P54936
961
108794
T809
F
A
Y
P
I
P
H
T
T
R
P
P
R
K
D
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
H404
E
K
S
G
V
E
Y
H
F
V
L
R
S
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
66.3
93.4
N.A.
93.4
30.2
N.A.
66.1
36.2
72
36.8
33.5
31.9
42.3
26.9
46
Protein Similarity:
100
82.9
81.7
94.7
N.A.
94.9
43.5
N.A.
80.5
53.1
82.1
55
51.3
43.7
61.9
41.7
65.8
P-Site Identity:
100
100
66.6
93.3
N.A.
100
0
N.A.
66.6
6.6
66.6
40
6.6
6.6
40
0
46.6
P-Site Similarity:
100
100
80
93.3
N.A.
100
20
N.A.
80
20
80
53.3
13.3
33.3
60
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
14
0
0
7
0
0
0
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
27
0
0
0
0
7
0
7
7
0
7
7
14
% D
% Glu:
67
7
34
0
7
20
7
7
0
0
0
7
14
47
0
% E
% Phe:
14
0
0
0
0
0
0
0
67
0
0
0
0
7
14
% F
% Gly:
0
0
0
67
0
27
7
0
7
0
14
0
20
0
0
% G
% His:
0
0
0
0
0
0
14
14
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
14
0
0
0
0
14
0
0
0
0
0
% I
% Lys:
0
20
7
0
14
14
0
14
0
0
0
14
7
14
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% M
% Asn:
0
0
0
0
0
0
7
7
0
7
0
0
7
0
0
% N
% Pro:
7
0
14
20
0
14
0
0
0
0
14
14
0
0
0
% P
% Gln:
0
0
0
14
47
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
40
0
0
7
0
0
0
0
20
0
60
7
0
0
% R
% Ser:
0
7
7
0
0
14
0
34
0
0
54
0
20
7
0
% S
% Thr:
14
0
0
0
0
0
0
14
14
0
7
0
0
0
0
% T
% Val:
0
0
0
0
14
0
0
0
7
54
0
0
0
0
7
% V
% Trp:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
0
0
0
67
0
0
0
0
7
7
14
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _