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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP2
All Species:
11.52
Human Site:
Y139
Identified Species:
18.1
UniProt:
Q14168
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14168
NP_005365.3
576
64581
Y139
D
S
V
A
S
K
T
Y
E
T
P
P
P
S
P
Chimpanzee
Pan troglodytes
XP_511538
656
72549
Y219
D
S
V
A
S
K
T
Y
E
T
P
P
P
S
P
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
Y146
D
I
V
A
S
K
C
Y
D
S
P
P
S
S
P
Dog
Lupus familis
XP_548068
552
61535
G123
E
T
P
P
P
S
P
G
L
D
P
T
F
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV34
552
61537
G123
E
T
P
P
P
S
P
G
L
D
P
T
F
S
N
Rat
Rattus norvegicus
Q62915
909
103240
Y452
H
V
V
A
H
E
V
Y
S
D
E
A
L
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
V123
S
S
V
N
N
Q
I
V
P
V
D
A
I
R
I
Chicken
Gallus gallus
Q5ZJ00
468
52501
M97
L
N
D
K
Q
S
C
M
V
A
R
I
F
H
G
Frog
Xenopus laevis
NP_001087762
532
59489
I123
D
A
V
R
M
V
G
I
R
K
S
A
G
E
H
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
R141
E
D
S
V
K
I
I
R
L
V
K
N
K
E
P
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
C96
K
L
N
D
K
Q
R
C
S
V
A
R
I
L
H
Fruit Fly
Dros. melanogaster
Q24210
898
100893
V394
D
R
I
A
A
T
V
V
T
S
N
G
R
A
P
Honey Bee
Apis mellifera
XP_391909
602
67965
E162
D
A
V
V
E
R
K
E
A
P
P
S
K
P
E
Nematode Worm
Caenorhab. elegans
P54936
961
108794
R476
D
V
V
V
C
E
I
R
D
P
K
N
E
A
S
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
Y130
F
E
D
H
T
Q
D
Y
Y
T
P
D
F
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
66.3
93.4
N.A.
93.4
30.2
N.A.
66.1
36.2
72
36.8
33.5
31.9
42.3
26.9
46
Protein Similarity:
100
82.9
81.7
94.7
N.A.
94.9
43.5
N.A.
80.5
53.1
82.1
55
51.3
43.7
61.9
41.7
65.8
P-Site Identity:
100
100
66.6
13.3
N.A.
13.3
20
N.A.
13.3
0
13.3
6.6
0
20
20
13.3
26.6
P-Site Similarity:
100
100
80
26.6
N.A.
26.6
26.6
N.A.
26.6
6.6
20
13.3
6.6
46.6
33.3
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
34
7
0
0
0
7
7
7
20
0
14
0
% A
% Cys:
0
0
0
0
7
0
14
7
0
0
0
0
0
0
0
% C
% Asp:
47
7
14
7
0
0
7
0
14
20
7
7
0
0
0
% D
% Glu:
20
7
0
0
7
14
0
7
14
0
7
0
7
14
7
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
27
0
0
% F
% Gly:
0
0
0
0
0
0
7
14
0
0
0
7
7
0
7
% G
% His:
7
0
0
7
7
0
0
0
0
0
0
0
0
7
14
% H
% Ile:
0
7
7
0
0
7
20
7
0
0
0
7
14
0
7
% I
% Lys:
7
0
0
7
14
20
7
0
0
7
14
0
14
0
0
% K
% Leu:
7
7
0
0
0
0
0
0
20
0
0
0
7
7
0
% L
% Met:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
7
7
0
0
0
0
0
7
14
0
7
14
% N
% Pro:
0
0
14
14
14
0
14
0
7
14
47
20
14
7
40
% P
% Gln:
0
0
0
0
7
20
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
7
0
7
7
14
7
0
7
7
7
14
0
% R
% Ser:
7
20
7
0
20
20
0
0
14
14
7
7
7
34
7
% S
% Thr:
0
14
0
0
7
7
14
0
7
20
0
14
0
0
0
% T
% Val:
0
14
54
20
0
7
14
14
7
20
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _