KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP2
All Species:
36.36
Human Site:
Y363
Identified Species:
57.14
UniProt:
Q14168
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14168
NP_005365.3
576
64581
Y363
D
R
H
E
L
L
I
Y
E
E
V
A
R
M
P
Chimpanzee
Pan troglodytes
XP_511538
656
72549
Y443
D
R
H
E
L
L
I
Y
E
E
V
A
R
M
P
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
Y369
D
R
H
E
I
Q
I
Y
E
E
V
A
K
M
P
Dog
Lupus familis
XP_548068
552
61535
Y339
D
R
H
E
L
L
I
Y
E
E
V
A
R
M
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV34
552
61537
Y339
D
R
H
E
L
L
I
Y
E
E
V
A
R
M
P
Rat
Rattus norvegicus
Q62915
909
103240
Y696
F
G
K
K
K
K
Q
Y
K
D
K
Y
L
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
Y327
D
R
H
E
I
Q
I
Y
E
E
V
A
K
M
P
Chicken
Gallus gallus
Q5ZJ00
468
52501
D266
A
K
H
S
S
I
F
D
Q
L
D
V
V
S
Y
Frog
Xenopus laevis
NP_001087762
532
59489
Y319
D
R
H
E
L
L
I
Y
E
E
V
A
R
M
P
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
V357
D
V
P
T
Y
E
E
V
T
T
Y
R
R
K
H
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
D265
A
K
H
S
S
I
F
D
Q
L
D
V
I
S
Y
Fruit Fly
Dros. melanogaster
Q24210
898
100893
T695
F
D
T
L
D
V
V
T
Y
E
E
V
V
K
V
Honey Bee
Apis mellifera
XP_391909
602
67965
Y388
D
S
A
E
L
L
L
Y
E
E
V
A
R
M
P
Nematode Worm
Caenorhab. elegans
P54936
961
108794
L748
K
Y
Y
T
T
K
Y
L
Q
K
H
S
A
L
F
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
Y343
D
R
S
D
I
V
I
Y
E
E
V
Q
E
M
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
66.3
93.4
N.A.
93.4
30.2
N.A.
66.1
36.2
72
36.8
33.5
31.9
42.3
26.9
46
Protein Similarity:
100
82.9
81.7
94.7
N.A.
94.9
43.5
N.A.
80.5
53.1
82.1
55
51.3
43.7
61.9
41.7
65.8
P-Site Identity:
100
100
80
100
N.A.
100
6.6
N.A.
80
6.6
100
13.3
6.6
6.6
80
0
60
P-Site Similarity:
100
100
93.3
100
N.A.
100
26.6
N.A.
93.3
26.6
100
13.3
26.6
20
86.6
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
0
0
0
0
0
0
0
0
54
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
7
0
7
7
0
0
14
0
7
14
0
0
0
0
% D
% Glu:
0
0
0
54
0
7
7
0
60
67
7
0
7
0
0
% E
% Phe:
14
0
0
0
0
0
14
0
0
0
0
0
0
0
7
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
60
0
0
0
0
0
0
0
7
0
0
0
7
% H
% Ile:
0
0
0
0
20
14
54
0
0
0
0
0
7
0
0
% I
% Lys:
7
14
7
7
7
14
0
0
7
7
7
0
14
14
7
% K
% Leu:
0
0
0
7
40
40
7
7
0
14
0
0
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
60
% P
% Gln:
0
0
0
0
0
14
7
0
20
0
0
7
0
0
0
% Q
% Arg:
0
54
0
0
0
0
0
0
0
0
0
7
47
0
0
% R
% Ser:
0
7
7
14
14
0
0
0
0
0
0
7
0
14
0
% S
% Thr:
0
0
7
14
7
0
0
7
7
7
0
0
0
0
0
% T
% Val:
0
7
0
0
0
14
7
7
0
0
60
20
14
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
7
0
7
67
7
0
7
7
0
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _