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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPP2 All Species: 30.61
Human Site: Y423 Identified Species: 48.1
UniProt: Q14168 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14168 NP_005365.3 576 64581 Y423 S E R E G Q G Y S F V S R G E
Chimpanzee Pan troglodytes XP_511538 656 72549 Y503 S E R E G Q G Y S F V S R G E
Rhesus Macaque Macaca mulatta XP_001096776 582 65885 Y429 D E K D G Q A Y K F V S R S E
Dog Lupus familis XP_548068 552 61535 Y399 S E R E G Q G Y S F V S R S E
Cat Felis silvestris
Mouse Mus musculus Q9WV34 552 61537 Y399 S E R E G Q G Y S F V S R G E
Rat Rattus norvegicus Q62915 909 103240 H756 R F A Y P I P H T T R P P K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507958 540 61012 Y387 D E K D G Q A Y K F V S R A E
Chicken Gallus gallus Q5ZJ00 468 52501 N326 T T R P Q K K N E V D G K D Y
Frog Xenopus laevis NP_001087762 532 59489 Y379 G E W D G Q S Y S F V T R A E
Zebra Danio Brachydanio rerio Q6P0D7 576 65174 Y417 Q E S E G V E Y H F I S K N L
Tiger Blowfish Takifugu rubipres P49697 467 52590 G325 T T R P Q R K G D A N G E E Y
Fruit Fly Dros. melanogaster Q24210 898 100893 E755 R P A K P E E E N G R S Y Y F
Honey Bee Apis mellifera XP_391909 602 67965 Y448 L E E D G K S Y W F I D R E S
Nematode Worm Caenorhab. elegans P54936 961 108794 H808 R F A Y P I P H T T R P P R K
Sea Urchin Strong. purpuratus XP_791632 556 63023 Y403 G E K S G V E Y H F V L R S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.5 66.3 93.4 N.A. 93.4 30.2 N.A. 66.1 36.2 72 36.8 33.5 31.9 42.3 26.9 46
Protein Similarity: 100 82.9 81.7 94.7 N.A. 94.9 43.5 N.A. 80.5 53.1 82.1 55 51.3 43.7 61.9 41.7 65.8
P-Site Identity: 100 100 60 93.3 N.A. 100 0 N.A. 60 6.6 60 40 6.6 6.6 33.3 0 40
P-Site Similarity: 100 100 73.3 93.3 N.A. 100 20 N.A. 73.3 26.6 73.3 53.3 20 26.6 53.3 20 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 0 0 14 0 0 7 0 0 0 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 0 27 0 0 0 0 7 0 7 7 0 7 7 % D
% Glu: 0 67 7 34 0 7 20 7 7 0 0 0 7 14 47 % E
% Phe: 0 14 0 0 0 0 0 0 0 67 0 0 0 0 7 % F
% Gly: 14 0 0 0 67 0 27 7 0 7 0 14 0 20 0 % G
% His: 0 0 0 0 0 0 0 14 14 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 14 0 0 0 0 14 0 0 0 0 % I
% Lys: 0 0 20 7 0 14 14 0 14 0 0 0 14 7 14 % K
% Leu: 7 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 7 0 7 0 0 7 0 % N
% Pro: 0 7 0 14 20 0 14 0 0 0 0 14 14 0 0 % P
% Gln: 7 0 0 0 14 47 0 0 0 0 0 0 0 0 0 % Q
% Arg: 20 0 40 0 0 7 0 0 0 0 20 0 60 7 0 % R
% Ser: 27 0 7 7 0 0 14 0 34 0 0 54 0 20 7 % S
% Thr: 14 14 0 0 0 0 0 0 14 14 0 7 0 0 0 % T
% Val: 0 0 0 0 0 14 0 0 0 7 54 0 0 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 14 0 0 0 67 0 0 0 0 7 7 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _