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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLA2 All Species: 30
Human Site: S147 Identified Species: 47.14
UniProt: Q14181 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14181 NP_002680.2 598 65948 S147 R S P H Q L L S P S S F S P S
Chimpanzee Pan troglodytes XP_508549 598 65915 S147 R S P H Q L L S P S S F S P S
Rhesus Macaque Macaca mulatta XP_001113977 598 65971 S147 R S P H Q L L S P S S F S P S
Dog Lupus familis XP_533234 595 65743 S143 R S P H Q L L S P S S F S P S
Cat Felis silvestris
Mouse Mus musculus P33611 600 66249 S147 R S P R Q L L S P S S F S P S
Rat Rattus norvegicus O89043 600 66618 S147 R S P H Q L L S P S S F S P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519697 439 48232 K16 T P E T P R S K R I V S T R S
Chicken Gallus gallus
Frog Xenopus laevis NP_001086972 598 66827 S147 R S P H V L F S P T S F S P S
Zebra Danio Brachydanio rerio NP_955875 599 66656 S147 A S P S L M L S P A S F S P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VB62 609 66952 A170 E T P S N S V A G K P G D I V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21625 581 64085 L132 A K L E G H F L D F S P F P G
Sea Urchin Strong. purpuratus XP_780208 604 66528 A153 E E D I T S S A G S P S L T A
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130410 626 69135 I153 A K T N A D R I T P F A T R V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176930 620 69024 P148 K S V G H V T P F G S R I E K
Baker's Yeast Sacchar. cerevisiae P38121 705 78756 A200 T S R Q N V P A G E I L D S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.1 88.1 N.A. 83 84.3 N.A. 57.8 N.A. 64.8 57.4 N.A. 29.8 N.A. 25.5 43.3
Protein Similarity: 100 100 98.4 93.8 N.A. 90.1 91 N.A. 66.7 N.A. 80 75.2 N.A. 49.4 N.A. 47.6 62.9
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 6.6 N.A. 80 66.6 N.A. 6.6 N.A. 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 13.3 N.A. 86.6 80 N.A. 26.6 N.A. 13.3 20
Percent
Protein Identity: N.A. 28.5 N.A. 30.3 25.1 N.A.
Protein Similarity: N.A. 47.4 N.A. 50 43.4 N.A.
P-Site Identity: N.A. 0 N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 7 0 0 20 0 7 0 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 7 0 0 7 0 0 0 14 0 0 % D
% Glu: 14 7 7 7 0 0 0 0 0 7 0 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 14 0 7 7 7 54 7 0 0 % F
% Gly: 0 0 0 7 7 0 0 0 20 7 0 7 0 0 7 % G
% His: 0 0 0 40 7 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 7 0 7 7 0 7 7 0 % I
% Lys: 7 14 0 0 0 0 0 7 0 7 0 0 0 0 7 % K
% Leu: 0 0 7 0 7 47 47 7 0 0 0 7 7 0 7 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 14 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 7 60 0 7 0 7 7 54 7 14 7 0 60 0 % P
% Gln: 0 0 0 7 40 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 47 0 7 7 0 7 7 0 7 0 0 7 0 14 0 % R
% Ser: 0 67 0 14 0 14 14 54 0 47 67 14 54 7 60 % S
% Thr: 14 7 7 7 7 0 7 0 7 7 0 0 14 7 0 % T
% Val: 0 0 7 0 7 14 7 0 0 0 7 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _