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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA2
All Species:
32.12
Human Site:
S158
Identified Species:
50.48
UniProt:
Q14181
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14181
NP_002680.2
598
65948
S158
F
S
P
S
A
T
P
S
Q
K
Y
N
S
R
S
Chimpanzee
Pan troglodytes
XP_508549
598
65915
S158
F
S
P
S
A
T
P
S
Q
K
Y
N
S
R
S
Rhesus Macaque
Macaca mulatta
XP_001113977
598
65971
S158
F
S
P
S
A
T
P
S
Q
K
Y
N
S
R
S
Dog
Lupus familis
XP_533234
595
65743
S154
F
S
P
S
A
T
P
S
Q
K
Y
S
S
R
N
Cat
Felis silvestris
Mouse
Mus musculus
P33611
600
66249
S158
F
S
P
S
A
T
P
S
Q
K
Y
T
S
R
T
Rat
Rattus norvegicus
O89043
600
66618
S158
F
S
P
S
A
T
P
S
Q
K
Y
S
S
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519697
439
48232
L27
S
T
R
S
P
H
L
L
F
S
P
T
S
F
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086972
598
66827
S158
F
S
P
S
A
T
P
S
Q
K
Y
G
S
R
T
Zebra Danio
Brachydanio rerio
NP_955875
599
66656
S158
F
S
P
S
A
T
P
S
Q
K
Y
G
M
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB62
609
66952
G181
G
D
I
V
D
T
F
G
H
P
K
L
L
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21625
581
64085
N143
P
F
P
G
S
P
A
N
E
K
F
L
K
R
A
Sea Urchin
Strong. purpuratus
XP_780208
604
66528
Q164
S
L
T
A
T
P
S
Q
K
Y
S
S
R
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130410
626
69135
T164
A
T
R
V
N
K
F
T
Q
Q
Y
V
L
N
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176930
620
69024
K159
R
I
E
K
F
V
V
K
F
N
V
G
N
V
A
Baker's Yeast
Sacchar. cerevisiae
P38121
705
78756
N211
L
D
S
L
N
P
E
N
I
E
I
S
S
G
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.1
88.1
N.A.
83
84.3
N.A.
57.8
N.A.
64.8
57.4
N.A.
29.8
N.A.
25.5
43.3
Protein Similarity:
100
100
98.4
93.8
N.A.
90.1
91
N.A.
66.7
N.A.
80
75.2
N.A.
49.4
N.A.
47.6
62.9
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
20
N.A.
86.6
80
N.A.
6.6
N.A.
20
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
26.6
N.A.
93.3
80
N.A.
6.6
N.A.
53.3
20
Percent
Protein Identity:
N.A.
28.5
N.A.
30.3
25.1
N.A.
Protein Similarity:
N.A.
47.4
N.A.
50
43.4
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
54
0
7
0
0
0
0
0
0
7
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
0
0
7
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
7
0
0
0
7
0
7
7
0
0
0
0
0
% E
% Phe:
54
7
0
0
7
0
14
0
14
0
7
0
0
7
0
% F
% Gly:
7
0
0
7
0
0
0
7
0
0
0
20
0
7
14
% G
% His:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
0
0
0
0
7
0
7
0
0
0
0
% I
% Lys:
0
0
0
7
0
7
0
7
7
60
7
0
7
0
7
% K
% Leu:
7
7
0
7
0
0
7
7
0
0
0
14
14
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
14
0
0
14
0
7
0
20
7
7
14
% N
% Pro:
7
0
60
0
7
20
54
0
0
7
7
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
60
7
0
0
0
0
0
% Q
% Arg:
7
0
14
0
0
0
0
0
0
0
0
0
7
60
0
% R
% Ser:
14
54
7
60
7
0
7
54
0
7
7
27
60
7
27
% S
% Thr:
0
14
7
0
7
60
0
7
0
0
0
14
0
0
20
% T
% Val:
0
0
0
14
0
7
7
0
0
0
7
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
60
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _