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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA2
All Species:
40.61
Human Site:
S269
Identified Species:
63.81
UniProt:
Q14181
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14181
NP_002680.2
598
65948
S269
N
G
K
L
N
N
K
S
V
I
L
E
G
D
R
Chimpanzee
Pan troglodytes
XP_508549
598
65915
S269
N
G
K
L
N
N
K
S
V
I
L
E
G
D
R
Rhesus Macaque
Macaca mulatta
XP_001113977
598
65971
S269
N
G
K
L
N
N
K
S
V
I
L
E
G
D
R
Dog
Lupus familis
XP_533234
595
65743
S265
N
G
K
L
N
S
K
S
V
I
L
E
G
D
R
Cat
Felis silvestris
Mouse
Mus musculus
P33611
600
66249
S269
N
G
K
L
N
S
K
S
V
I
L
E
G
D
Q
Rat
Rattus norvegicus
O89043
600
66618
S269
N
G
R
L
N
S
K
S
V
I
L
E
G
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519697
439
48232
Q138
E
P
V
T
V
L
G
Q
I
G
C
D
S
N
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086972
598
66827
S269
N
G
K
L
N
S
K
S
V
I
L
E
G
D
R
Zebra Danio
Brachydanio rerio
NP_955875
599
66656
S269
N
G
K
L
N
A
Q
S
V
L
L
E
A
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB62
609
66952
M292
L
D
A
H
S
A
F
M
A
V
L
D
D
D
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21625
581
64085
H254
D
N
E
K
F
G
E
H
S
V
A
L
M
I
N
Sea Urchin
Strong. purpuratus
XP_780208
604
66528
S275
N
G
R
L
N
A
Q
S
V
M
M
E
G
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130410
626
69135
S275
E
G
H
L
N
E
K
S
I
L
L
Q
G
S
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176930
620
69024
S270
E
G
H
L
N
D
K
S
I
L
L
Q
S
S
A
Baker's Yeast
Sacchar. cerevisiae
P38121
705
78756
R322
S
L
S
L
E
T
S
R
M
G
G
V
G
R
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.1
88.1
N.A.
83
84.3
N.A.
57.8
N.A.
64.8
57.4
N.A.
29.8
N.A.
25.5
43.3
Protein Similarity:
100
100
98.4
93.8
N.A.
90.1
91
N.A.
66.7
N.A.
80
75.2
N.A.
49.4
N.A.
47.6
62.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
0
N.A.
93.3
60
N.A.
13.3
N.A.
0
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
N.A.
100
80
N.A.
33.3
N.A.
26.6
80
Percent
Protein Identity:
N.A.
28.5
N.A.
30.3
25.1
N.A.
Protein Similarity:
N.A.
47.4
N.A.
50
43.4
N.A.
P-Site Identity:
N.A.
46.6
N.A.
40
20
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
66.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
20
0
0
7
0
7
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
7
7
0
0
0
7
0
0
0
0
0
14
7
54
0
% D
% Glu:
20
0
7
0
7
7
7
0
0
0
0
60
0
0
0
% E
% Phe:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
74
0
0
0
7
7
0
0
14
7
0
67
7
7
% G
% His:
0
0
14
7
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
20
47
0
0
0
7
0
% I
% Lys:
0
0
47
7
0
0
60
0
0
0
0
0
0
0
0
% K
% Leu:
7
7
0
80
0
7
0
0
0
20
74
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
7
7
7
7
0
7
0
0
% M
% Asn:
60
7
0
0
74
20
0
0
0
0
0
0
0
7
7
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
14
7
0
0
0
14
0
0
14
% Q
% Arg:
0
0
14
0
0
0
0
7
0
0
0
0
0
7
47
% R
% Ser:
7
0
7
0
7
27
7
74
7
0
0
0
14
20
0
% S
% Thr:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
7
0
0
0
60
14
0
7
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _