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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA2
All Species:
25.45
Human Site:
S280
Identified Species:
40
UniProt:
Q14181
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14181
NP_002680.2
598
65948
S280
E
G
D
R
E
H
S
S
G
A
Q
I
P
V
D
Chimpanzee
Pan troglodytes
XP_508549
598
65915
S280
E
G
D
R
E
H
S
S
G
A
Q
I
P
V
D
Rhesus Macaque
Macaca mulatta
XP_001113977
598
65971
S280
E
G
D
R
E
H
S
S
G
A
Q
I
P
V
D
Dog
Lupus familis
XP_533234
595
65743
S276
E
G
D
R
E
H
S
S
G
A
Q
I
P
V
D
Cat
Felis silvestris
Mouse
Mus musculus
P33611
600
66249
Y280
E
G
D
Q
E
H
S
Y
G
A
Q
I
P
V
D
Rat
Rattus norvegicus
O89043
600
66618
S280
E
G
D
R
E
H
S
S
G
A
Q
I
P
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519697
439
48232
P149
D
S
N
G
K
L
N
P
K
S
V
I
L
E
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086972
598
66827
A280
E
G
D
R
E
H
S
A
G
M
Q
V
P
V
D
Zebra Danio
Brachydanio rerio
NP_955875
599
66656
G280
E
A
G
Q
E
Q
G
G
R
Q
V
P
V
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB62
609
66952
M303
D
D
D
V
E
D
E
M
D
P
T
L
T
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21625
581
64085
G265
L
M
I
N
D
E
D
G
T
M
I
R
M
D
F
Sea Urchin
Strong. purpuratus
XP_780208
604
66528
A286
E
G
S
V
E
T
S
A
G
K
Q
V
A
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130410
626
69135
R286
Q
G
S
V
E
H
S
R
G
Q
C
V
R
L
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176930
620
69024
S281
Q
S
S
A
E
R
T
S
G
Q
R
V
P
V
D
Baker's Yeast
Sacchar. cerevisiae
P38121
705
78756
D333
V
G
R
R
V
R
L
D
L
S
Q
V
N
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.1
88.1
N.A.
83
84.3
N.A.
57.8
N.A.
64.8
57.4
N.A.
29.8
N.A.
25.5
43.3
Protein Similarity:
100
100
98.4
93.8
N.A.
90.1
91
N.A.
66.7
N.A.
80
75.2
N.A.
49.4
N.A.
47.6
62.9
P-Site Identity:
100
100
100
100
N.A.
86.6
100
N.A.
6.6
N.A.
80
13.3
N.A.
13.3
N.A.
0
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
40
N.A.
93.3
20
N.A.
40
N.A.
6.6
60
Percent
Protein Identity:
N.A.
28.5
N.A.
30.3
25.1
N.A.
Protein Similarity:
N.A.
47.4
N.A.
50
43.4
N.A.
P-Site Identity:
N.A.
40
N.A.
40
20
N.A.
P-Site Similarity:
N.A.
60
N.A.
66.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
14
0
40
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
14
7
54
0
7
7
7
7
7
0
0
0
0
14
60
% D
% Glu:
60
0
0
0
80
7
7
0
0
0
0
0
0
14
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
67
7
7
0
0
7
14
67
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
7
47
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
0
7
7
0
0
0
0
0
% K
% Leu:
7
0
0
0
0
7
7
0
7
0
0
7
7
14
14
% L
% Met:
0
7
0
0
0
0
0
7
0
14
0
0
7
0
0
% M
% Asn:
0
0
7
7
0
0
7
0
0
0
0
0
7
0
7
% N
% Pro:
0
0
0
0
0
0
0
7
0
7
0
7
54
0
0
% P
% Gln:
14
0
0
14
0
7
0
0
0
20
60
0
0
0
0
% Q
% Arg:
0
0
7
47
0
14
0
7
7
0
7
7
7
0
0
% R
% Ser:
0
14
20
0
0
0
60
40
0
14
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
7
7
0
7
0
7
0
7
0
0
% T
% Val:
7
0
0
20
7
0
0
0
0
0
14
34
7
60
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _