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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA2
All Species:
14.85
Human Site:
S446
Identified Species:
23.33
UniProt:
Q14181
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14181
NP_002680.2
598
65948
S446
P
F
S
Y
S
D
L
S
R
E
D
K
K
Q
V
Chimpanzee
Pan troglodytes
XP_508549
598
65915
S446
P
F
S
Y
S
D
L
S
R
E
D
K
K
Q
V
Rhesus Macaque
Macaca mulatta
XP_001113977
598
65971
S446
P
F
S
Y
S
D
L
S
R
E
D
K
K
Q
V
Dog
Lupus familis
XP_533234
595
65743
A442
P
F
S
Y
S
D
L
A
R
E
D
R
K
R
V
Cat
Felis silvestris
Mouse
Mus musculus
P33611
600
66249
S446
P
F
T
F
S
E
L
S
R
E
D
K
K
R
V
Rat
Rattus norvegicus
O89043
600
66618
P446
P
F
T
F
S
E
L
P
R
E
D
K
K
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519697
439
48232
G292
C
L
R
T
I
I
E
G
T
R
S
S
G
S
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086972
598
66827
A446
P
F
S
C
F
E
P
A
K
E
D
K
E
R
V
Zebra Danio
Brachydanio rerio
NP_955875
599
66656
I446
Q
P
P
F
N
L
T
I
S
K
E
D
T
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB62
609
66952
A458
V
Y
P
T
P
P
P
A
L
R
R
T
Y
P
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21625
581
64085
L428
P
F
Q
Q
N
R
K
L
D
K
I
K
K
E
L
Sea Urchin
Strong. purpuratus
XP_780208
604
66528
I448
P
Q
P
P
Y
S
E
I
K
N
Q
P
K
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130410
626
69135
T473
D
L
N
L
L
E
D
T
T
H
Q
I
T
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176930
620
69024
D468
P
F
D
I
H
I
P
D
L
E
H
Q
M
T
S
Baker's Yeast
Sacchar. cerevisiae
P38121
705
78756
L508
A
S
L
I
R
K
A
L
Q
L
P
K
R
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.1
88.1
N.A.
83
84.3
N.A.
57.8
N.A.
64.8
57.4
N.A.
29.8
N.A.
25.5
43.3
Protein Similarity:
100
100
98.4
93.8
N.A.
90.1
91
N.A.
66.7
N.A.
80
75.2
N.A.
49.4
N.A.
47.6
62.9
P-Site Identity:
100
100
100
80
N.A.
73.3
66.6
N.A.
0
N.A.
46.6
0
N.A.
0
N.A.
26.6
20
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
0
N.A.
80
26.6
N.A.
13.3
N.A.
53.3
33.3
Percent
Protein Identity:
N.A.
28.5
N.A.
30.3
25.1
N.A.
Protein Similarity:
N.A.
47.4
N.A.
50
43.4
N.A.
P-Site Identity:
N.A.
0
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
20
0
0
0
0
0
7
0
% A
% Cys:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
27
7
7
7
0
47
7
0
0
0
% D
% Glu:
0
0
0
0
0
27
14
0
0
54
7
0
7
7
0
% E
% Phe:
0
60
0
20
7
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
7
7
0
0
0
7
% H
% Ile:
0
0
0
14
7
14
0
14
0
0
7
7
0
0
0
% I
% Lys:
0
0
0
0
0
7
7
0
14
14
0
54
54
0
0
% K
% Leu:
0
14
7
7
7
7
40
14
14
7
0
0
0
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
7
0
14
0
0
0
0
7
0
0
0
7
7
% N
% Pro:
67
7
20
7
7
7
20
7
0
0
7
7
0
7
0
% P
% Gln:
7
7
7
7
0
0
0
0
7
0
14
7
0
20
0
% Q
% Arg:
0
0
7
0
7
7
0
0
40
14
7
7
7
34
7
% R
% Ser:
0
7
34
0
40
7
0
27
7
0
7
7
0
14
7
% S
% Thr:
0
0
14
14
0
0
7
7
14
0
0
7
14
7
0
% T
% Val:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
27
7
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _