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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA2
All Species:
23.64
Human Site:
T127
Identified Species:
37.14
UniProt:
Q14181
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14181
NP_002680.2
598
65948
T127
S
Q
K
R
A
I
S
T
P
E
T
P
L
T
K
Chimpanzee
Pan troglodytes
XP_508549
598
65915
T127
S
Q
K
R
A
I
S
T
P
E
T
P
L
T
K
Rhesus Macaque
Macaca mulatta
XP_001113977
598
65971
T127
S
Q
K
R
T
I
S
T
P
E
T
P
L
T
K
Dog
Lupus familis
XP_533234
595
65743
T123
S
Q
K
R
A
I
T
T
P
E
T
P
L
T
K
Cat
Felis silvestris
Mouse
Mus musculus
P33611
600
66249
T127
P
L
K
R
V
S
S
T
P
E
T
P
L
T
K
Rat
Rattus norvegicus
O89043
600
66618
T127
P
H
K
R
V
S
S
T
P
E
T
P
L
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519697
439
48232
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086972
598
66827
P127
Q
K
R
N
L
S
T
P
E
H
P
Q
S
K
R
Zebra Danio
Brachydanio rerio
NP_955875
599
66656
P127
Q
K
R
A
L
T
T
P
E
H
P
Q
S
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB62
609
66952
S150
A
A
L
F
S
P
A
S
Y
T
P
Q
S
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21625
581
64085
I112
L
S
G
D
P
D
D
I
E
K
P
S
H
H
L
Sea Urchin
Strong. purpuratus
XP_780208
604
66528
N133
T
T
P
D
N
V
T
N
K
R
T
P
L
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130410
626
69135
T133
G
S
S
I
S
E
L
T
P
L
A
S
D
R
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176930
620
69024
S128
L
H
P
D
P
F
D
S
I
S
R
S
R
D
Y
Baker's Yeast
Sacchar. cerevisiae
P38121
705
78756
S180
S
D
A
K
T
P
G
S
S
T
F
Q
T
P
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.1
88.1
N.A.
83
84.3
N.A.
57.8
N.A.
64.8
57.4
N.A.
29.8
N.A.
25.5
43.3
Protein Similarity:
100
100
98.4
93.8
N.A.
90.1
91
N.A.
66.7
N.A.
80
75.2
N.A.
49.4
N.A.
47.6
62.9
P-Site Identity:
100
100
93.3
93.3
N.A.
73.3
73.3
N.A.
0
N.A.
0
0
N.A.
6.6
N.A.
0
20
P-Site Similarity:
100
100
93.3
100
N.A.
73.3
73.3
N.A.
0
N.A.
26.6
26.6
N.A.
33.3
N.A.
6.6
46.6
Percent
Protein Identity:
N.A.
28.5
N.A.
30.3
25.1
N.A.
Protein Similarity:
N.A.
47.4
N.A.
50
43.4
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
7
20
0
7
0
0
0
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
20
0
7
14
0
0
0
0
0
7
7
0
% D
% Glu:
0
0
0
0
0
7
0
0
20
40
0
0
0
0
7
% E
% Phe:
0
0
0
7
0
7
0
0
0
0
7
0
0
0
0
% F
% Gly:
7
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
14
0
0
0
0
0
0
0
14
0
0
7
7
0
% H
% Ile:
0
0
0
7
0
27
0
7
7
0
0
0
0
0
0
% I
% Lys:
0
14
40
7
0
0
0
0
7
7
0
0
0
14
47
% K
% Leu:
14
7
7
0
14
0
7
0
0
7
0
0
47
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
14
0
14
0
14
14
0
14
47
0
27
47
0
7
7
% P
% Gln:
14
27
0
0
0
0
0
0
0
0
0
27
0
0
0
% Q
% Arg:
0
0
14
40
0
0
0
0
0
7
7
0
7
14
14
% R
% Ser:
34
14
7
0
14
20
34
20
7
7
0
20
20
0
0
% S
% Thr:
7
7
0
0
14
7
27
47
0
14
47
0
7
40
7
% T
% Val:
0
0
0
0
14
7
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _