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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA2
All Species:
20.61
Human Site:
T139
Identified Species:
32.38
UniProt:
Q14181
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14181
NP_002680.2
598
65948
T139
L
T
K
R
S
V
S
T
R
S
P
H
Q
L
L
Chimpanzee
Pan troglodytes
XP_508549
598
65915
T139
L
T
K
R
S
V
S
T
R
S
P
H
Q
L
L
Rhesus Macaque
Macaca mulatta
XP_001113977
598
65971
T139
L
T
K
R
S
V
S
T
R
S
P
H
Q
L
L
Dog
Lupus familis
XP_533234
595
65743
T135
L
T
K
R
T
M
S
T
R
S
P
H
Q
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P33611
600
66249
A139
L
T
K
R
S
V
A
A
R
S
P
R
Q
L
L
Rat
Rattus norvegicus
O89043
600
66618
T139
L
T
K
R
S
I
S
T
R
S
P
H
Q
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519697
439
48232
T8
S
S
Q
K
R
T
I
T
T
P
E
T
P
R
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086972
598
66827
N139
S
K
R
I
L
S
I
N
R
S
P
H
V
L
F
Zebra Danio
Brachydanio rerio
NP_955875
599
66656
L139
S
K
R
G
V
A
R
L
A
S
P
S
L
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB62
609
66952
L162
S
A
K
R
K
A
G
L
E
T
P
S
N
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21625
581
64085
I124
H
H
L
T
N
S
A
I
A
K
L
E
G
H
F
Sea Urchin
Strong. purpuratus
XP_780208
604
66528
K145
L
R
E
H
N
I
K
K
E
E
D
I
T
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130410
626
69135
V145
D
R
P
S
S
S
R
V
A
K
T
N
A
D
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176930
620
69024
G140
R
D
Y
G
Y
S
T
G
K
S
V
G
H
V
T
Baker's Yeast
Sacchar. cerevisiae
P38121
705
78756
T192
T
P
T
T
N
T
P
T
T
S
R
Q
N
V
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.1
88.1
N.A.
83
84.3
N.A.
57.8
N.A.
64.8
57.4
N.A.
29.8
N.A.
25.5
43.3
Protein Similarity:
100
100
98.4
93.8
N.A.
90.1
91
N.A.
66.7
N.A.
80
75.2
N.A.
49.4
N.A.
47.6
62.9
P-Site Identity:
100
100
100
86.6
N.A.
80
93.3
N.A.
6.6
N.A.
33.3
20
N.A.
20
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
100
N.A.
26.6
N.A.
40
33.3
N.A.
33.3
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
28.5
N.A.
30.3
25.1
N.A.
Protein Similarity:
N.A.
47.4
N.A.
50
43.4
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
14
14
7
20
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
0
0
0
0
0
7
0
0
7
0
% D
% Glu:
0
0
7
0
0
0
0
0
14
7
7
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% F
% Gly:
0
0
0
14
0
0
7
7
0
0
0
7
7
0
0
% G
% His:
7
7
0
7
0
0
0
0
0
0
0
40
7
7
0
% H
% Ile:
0
0
0
7
0
14
14
7
0
0
0
7
0
0
0
% I
% Lys:
0
14
47
7
7
0
7
7
7
14
0
0
0
0
0
% K
% Leu:
47
0
7
0
7
0
0
14
0
0
7
0
7
47
47
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
20
0
0
7
0
0
0
7
14
0
0
% N
% Pro:
0
7
7
0
0
0
7
0
0
7
60
0
7
0
7
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
7
40
0
0
% Q
% Arg:
7
14
14
47
7
0
14
0
47
0
7
7
0
7
7
% R
% Ser:
27
7
0
7
40
27
34
0
0
67
0
14
0
14
14
% S
% Thr:
7
40
7
14
7
14
7
47
14
7
7
7
7
0
7
% T
% Val:
0
0
0
0
7
27
0
7
0
0
7
0
7
14
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _