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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA2
All Species:
27.27
Human Site:
T491
Identified Species:
42.86
UniProt:
Q14181
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14181
NP_002680.2
598
65948
T491
E
I
S
S
S
S
G
T
S
D
R
F
S
R
I
Chimpanzee
Pan troglodytes
XP_508549
598
65915
T491
E
I
S
S
S
S
G
T
S
D
R
F
S
R
I
Rhesus Macaque
Macaca mulatta
XP_001113977
598
65971
T491
E
I
S
S
S
S
G
T
S
D
R
F
S
R
I
Dog
Lupus familis
XP_533234
595
65743
T487
E
I
S
S
A
S
G
T
S
D
R
L
S
R
I
Cat
Felis silvestris
Mouse
Mus musculus
P33611
600
66249
T491
E
I
F
S
S
S
G
T
S
D
R
F
S
R
V
Rat
Rattus norvegicus
O89043
600
66618
T491
E
I
C
S
S
S
G
T
S
D
R
F
S
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519697
439
48232
S337
R
Q
R
V
L
F
V
S
D
P
C
T
L
S
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086972
598
66827
A491
E
I
S
S
S
A
G
A
P
D
R
F
S
R
I
Zebra Danio
Brachydanio rerio
NP_955875
599
66656
G491
E
E
I
S
S
G
T
G
T
E
R
F
S
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB62
609
66952
G503
H
E
F
A
V
N
A
G
E
R
M
H
R
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21625
581
64085
Q473
E
F
H
R
S
A
N
Q
E
N
I
D
R
V
A
Sea Urchin
Strong. purpuratus
XP_780208
604
66528
S493
E
I
S
C
P
P
G
S
S
D
R
L
G
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130410
626
69135
P518
R
K
P
P
G
G
K
P
G
D
R
I
G
R
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176930
620
69024
P513
S
K
N
P
S
G
V
P
T
D
R
M
S
R
L
Baker's Yeast
Sacchar. cerevisiae
P38121
705
78756
S553
I
K
G
G
T
T
S
S
R
Y
R
L
D
R
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.1
88.1
N.A.
83
84.3
N.A.
57.8
N.A.
64.8
57.4
N.A.
29.8
N.A.
25.5
43.3
Protein Similarity:
100
100
98.4
93.8
N.A.
90.1
91
N.A.
66.7
N.A.
80
75.2
N.A.
49.4
N.A.
47.6
62.9
P-Site Identity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
0
N.A.
80
53.3
N.A.
6.6
N.A.
13.3
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
13.3
N.A.
86.6
66.6
N.A.
20
N.A.
26.6
66.6
Percent
Protein Identity:
N.A.
28.5
N.A.
30.3
25.1
N.A.
Protein Similarity:
N.A.
47.4
N.A.
50
43.4
N.A.
P-Site Identity:
N.A.
20
N.A.
33.3
13.3
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
53.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
14
7
7
0
0
0
0
0
7
7
% A
% Cys:
0
0
7
7
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
67
0
7
7
0
0
% D
% Glu:
67
14
0
0
0
0
0
0
14
7
0
0
0
0
0
% E
% Phe:
0
7
14
0
0
7
0
0
0
0
0
47
0
0
0
% F
% Gly:
0
0
7
7
7
20
54
14
7
0
0
0
14
0
0
% G
% His:
7
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
7
54
7
0
0
0
0
0
0
0
7
7
0
0
54
% I
% Lys:
0
20
0
0
0
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
7
0
0
0
0
0
0
20
7
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% M
% Asn:
0
0
7
0
0
7
7
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
7
14
7
7
0
14
7
7
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
14
0
7
7
0
0
0
0
7
7
80
0
14
80
0
% R
% Ser:
7
0
40
54
60
40
7
20
47
0
0
0
60
7
0
% S
% Thr:
0
0
0
0
7
7
7
40
14
0
0
7
0
0
0
% T
% Val:
0
0
0
7
7
0
14
0
0
0
0
0
0
7
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _