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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLA2 All Species: 33.03
Human Site: Y161 Identified Species: 51.9
UniProt: Q14181 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14181 NP_002680.2 598 65948 Y161 S A T P S Q K Y N S R S N R G
Chimpanzee Pan troglodytes XP_508549 598 65915 Y161 S A T P S Q K Y N S R S N R G
Rhesus Macaque Macaca mulatta XP_001113977 598 65971 Y161 S A T P S Q K Y N S R S N R G
Dog Lupus familis XP_533234 595 65743 Y157 S A T P S Q K Y S S R N N R G
Cat Felis silvestris
Mouse Mus musculus P33611 600 66249 Y161 S A T P S Q K Y T S R T N R G
Rat Rattus norvegicus O89043 600 66618 Y161 S A T P S Q K Y S S R T N R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519697 439 48232 P30 S P H L L F S P T S F S P S A
Chicken Gallus gallus
Frog Xenopus laevis NP_001086972 598 66827 Y161 S A T P S Q K Y G S R T N R G
Zebra Danio Brachydanio rerio NP_955875 599 66656 Y161 S A T P S Q K Y G M R G G R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VB62 609 66952 K184 V D T F G H P K L L A G S S W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21625 581 64085 F146 G S P A N E K F L K R A D P S
Sea Urchin Strong. purpuratus XP_780208 604 66528 S167 A T P S Q K Y S S R S K S G E
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130410 626 69135 Y167 V N K F T Q Q Y V L N A D N A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176930 620 69024 V162 K F V V K F N V G N V A A H A
Baker's Yeast Sacchar. cerevisiae P38121 705 78756 I214 L N P E N I E I S S G N P N V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.1 88.1 N.A. 83 84.3 N.A. 57.8 N.A. 64.8 57.4 N.A. 29.8 N.A. 25.5 43.3
Protein Similarity: 100 100 98.4 93.8 N.A. 90.1 91 N.A. 66.7 N.A. 80 75.2 N.A. 49.4 N.A. 47.6 62.9
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 20 N.A. 86.6 73.3 N.A. 6.6 N.A. 13.3 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 20 N.A. 93.3 73.3 N.A. 13.3 N.A. 53.3 26.6
Percent
Protein Identity: N.A. 28.5 N.A. 30.3 25.1 N.A.
Protein Similarity: N.A. 47.4 N.A. 50 43.4 N.A.
P-Site Identity: N.A. 13.3 N.A. 0 6.6 N.A.
P-Site Similarity: N.A. 40 N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 54 0 7 0 0 0 0 0 0 7 20 7 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 0 0 0 0 0 14 0 0 % D
% Glu: 0 0 0 7 0 7 7 0 0 0 0 0 0 0 7 % E
% Phe: 0 7 0 14 0 14 0 7 0 0 7 0 0 0 0 % F
% Gly: 7 0 0 0 7 0 0 0 20 0 7 14 7 7 54 % G
% His: 0 0 7 0 0 7 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 7 0 7 0 0 0 0 0 0 0 % I
% Lys: 7 0 7 0 7 7 60 7 0 7 0 7 0 0 0 % K
% Leu: 7 0 0 7 7 0 0 0 14 14 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 14 0 0 14 0 7 0 20 7 7 14 47 14 0 % N
% Pro: 0 7 20 54 0 0 7 7 0 0 0 0 14 7 0 % P
% Gln: 0 0 0 0 7 60 7 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 7 60 0 0 54 0 % R
% Ser: 60 7 0 7 54 0 7 7 27 60 7 27 14 14 7 % S
% Thr: 0 7 60 0 7 0 0 0 14 0 0 20 0 0 0 % T
% Val: 14 0 7 7 0 0 0 7 7 0 7 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 0 0 0 7 60 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _