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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA2
All Species:
30.3
Human Site:
Y528
Identified Species:
47.62
UniProt:
Q14181
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14181
NP_002680.2
598
65948
Y528
D
Y
E
S
F
Y
V
Y
A
Q
L
P
V
T
P
Chimpanzee
Pan troglodytes
XP_508549
598
65915
Y528
D
Y
E
S
F
Y
V
Y
A
Q
L
P
V
T
P
Rhesus Macaque
Macaca mulatta
XP_001113977
598
65971
Y528
D
Y
E
T
F
Y
V
Y
A
Q
L
P
V
T
P
Dog
Lupus familis
XP_533234
595
65743
Y524
D
Y
E
N
F
Y
I
Y
A
Q
L
P
I
T
P
Cat
Felis silvestris
Mouse
Mus musculus
P33611
600
66249
Y528
D
Y
E
N
F
Y
T
Y
A
Q
L
P
V
T
P
Rat
Rattus norvegicus
O89043
600
66618
Y528
D
Y
E
N
F
Y
T
Y
A
Q
L
P
V
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519697
439
48232
R374
S
S
S
S
G
S
D
R
F
S
R
I
L
K
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086972
598
66827
Y528
D
Y
E
A
L
Y
S
Y
T
P
M
P
V
T
P
Zebra Danio
Brachydanio rerio
NP_955875
599
66656
F528
D
Y
D
K
F
Q
Q
F
S
Q
M
S
L
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB62
609
66952
Y540
D
S
Q
L
A
L
K
Y
A
Q
L
K
Q
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21625
581
64085
V510
S
M
G
D
L
L
D
V
C
C
I
G
S
T
P
Sea Urchin
Strong. purpuratus
XP_780208
604
66528
Y530
D
Y
E
K
F
H
Q
Y
G
K
M
G
C
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130410
626
69135
A555
D
L
S
L
A
K
E
A
L
E
I
P
S
A
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176930
620
69024
A550
D
S
S
L
A
P
K
A
L
Q
I
S
S
I
P
Baker's Yeast
Sacchar. cerevisiae
P38121
705
78756
K590
K
P
K
D
V
S
T
K
K
E
T
N
D
M
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.1
88.1
N.A.
83
84.3
N.A.
57.8
N.A.
64.8
57.4
N.A.
29.8
N.A.
25.5
43.3
Protein Similarity:
100
100
98.4
93.8
N.A.
90.1
91
N.A.
66.7
N.A.
80
75.2
N.A.
49.4
N.A.
47.6
62.9
P-Site Identity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
6.6
N.A.
60
40
N.A.
40
N.A.
13.3
40
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
73.3
73.3
N.A.
46.6
N.A.
20
60
Percent
Protein Identity:
N.A.
28.5
N.A.
30.3
25.1
N.A.
Protein Similarity:
N.A.
47.4
N.A.
50
43.4
N.A.
P-Site Identity:
N.A.
20
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
20
0
0
14
47
0
0
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
7
0
0
7
0
0
% C
% Asp:
80
0
7
14
0
0
14
0
0
0
0
0
7
0
0
% D
% Glu:
0
0
54
0
0
0
7
0
0
14
0
0
0
0
7
% E
% Phe:
0
0
0
0
54
0
0
7
7
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
7
0
0
0
7
0
0
14
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
20
7
7
7
0
% I
% Lys:
7
0
7
14
0
7
14
7
7
7
0
7
0
7
0
% K
% Leu:
0
7
0
20
14
14
0
0
14
0
47
0
14
7
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
20
0
0
7
0
% M
% Asn:
0
0
0
20
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
7
0
0
0
7
0
0
0
7
0
54
0
0
87
% P
% Gln:
0
0
7
0
0
7
14
0
0
60
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% R
% Ser:
14
20
20
20
0
14
7
0
7
7
0
14
20
0
0
% S
% Thr:
0
0
0
7
0
0
20
0
7
0
7
0
0
60
0
% T
% Val:
0
0
0
0
7
0
20
7
0
0
0
0
40
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
60
0
0
0
47
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _