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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOC2A
All Species:
24.24
Human Site:
Y235
Identified Species:
53.33
UniProt:
Q14183
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14183
NP_003577.2
400
43959
Y235
A
L
R
G
I
S
C
Y
L
K
E
L
E
Q
A
Chimpanzee
Pan troglodytes
XP_511241
225
25469
T77
R
T
K
T
L
R
N
T
L
N
P
T
W
N
E
Rhesus Macaque
Macaca mulatta
XP_001106759
400
44001
Y235
A
L
R
G
I
S
C
Y
L
K
E
L
E
Q
A
Dog
Lupus familis
XP_547065
420
46541
Y255
A
L
R
G
I
S
C
Y
L
K
E
L
E
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNF0
405
44590
Y240
A
L
R
G
I
S
C
Y
L
K
E
L
E
Q
A
Rat
Rattus norvegicus
P70611
403
44571
Y238
A
L
R
G
I
S
C
Y
L
K
E
L
E
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507365
735
80912
P427
A
P
P
T
T
A
A
P
V
R
Q
Q
P
L
P
Chicken
Gallus gallus
P47191
424
47487
E261
D
F
G
H
V
T
E
E
W
R
D
L
Q
S
A
Frog
Xenopus laevis
NP_001086752
692
77694
Y536
S
V
R
G
M
A
L
Y
E
D
E
N
D
R
G
Zebra Danio
Brachydanio rerio
XP_691832
589
65198
Y432
G
A
R
G
I
T
L
Y
E
D
E
T
G
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21521
474
53246
D282
T
L
V
F
A
I
F
D
F
D
R
F
S
K
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.5
98.2
90.9
N.A.
94
94.2
N.A.
33.3
24
34.6
40
N.A.
23.4
N.A.
N.A.
N.A.
Protein Similarity:
100
49.2
98.2
92.1
N.A.
95.8
96.2
N.A.
42.1
38.2
45.5
51.4
N.A.
35.6
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
13.3
26.6
33.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
33.3
46.6
66.6
46.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
10
0
0
10
19
10
0
0
0
0
0
0
0
55
% A
% Cys:
0
0
0
0
0
0
46
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
10
0
28
10
0
10
0
10
% D
% Glu:
0
0
0
0
0
0
10
10
19
0
64
0
46
0
10
% E
% Phe:
0
10
0
10
0
0
10
0
10
0
0
10
0
0
0
% F
% Gly:
10
0
10
64
0
0
0
0
0
0
0
0
10
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
55
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
46
0
0
0
19
0
% K
% Leu:
0
55
0
0
10
0
19
0
55
0
0
55
0
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
10
0
10
0
% N
% Pro:
0
10
10
0
0
0
0
10
0
0
10
0
10
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
10
10
46
0
% Q
% Arg:
10
0
64
0
0
10
0
0
0
19
10
0
0
10
0
% R
% Ser:
10
0
0
0
0
46
0
0
0
0
0
0
10
10
0
% S
% Thr:
10
10
0
19
10
19
0
10
0
0
0
19
0
0
0
% T
% Val:
0
10
10
0
10
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _