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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIM2
All Species:
10
Human Site:
T585
Identified Species:
20
UniProt:
Q14190
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14190
NP_005060.1
667
73219
T585
P
E
C
C
A
P
P
T
P
E
A
P
G
A
P
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
T653
N
D
Y
D
N
S
P
T
A
L
S
R
I
S
S
Rhesus Macaque
Macaca mulatta
XP_001085660
634
69808
G557
P
P
A
P
E
P
P
G
A
P
P
Q
L
P
F
Dog
Lupus familis
XP_539058
766
85506
T653
N
D
Y
D
N
S
P
T
A
L
S
R
I
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61079
657
72494
E580
A
L
A
R
A
P
P
E
C
C
A
P
P
A
P
Rat
Rattus norvegicus
O35800
825
92301
S644
I
L
I
A
S
P
P
S
T
Q
V
P
Q
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512322
938
100601
K851
A
Y
A
P
R
A
G
K
A
E
A
G
P
V
G
Chicken
Gallus gallus
Q9YIB9
811
90524
T636
P
V
H
V
I
N
D
T
S
S
A
P
A
S
P
Frog
Xenopus laevis
Q9I8A9
805
90946
S630
P
V
H
M
M
K
E
S
T
S
A
P
V
S
P
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
P629
A
Q
V
I
S
P
A
P
S
P
V
P
L
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05709
697
76457
R618
D
V
A
T
S
M
I
R
P
F
S
A
N
S
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782984
820
91461
T591
T
G
S
P
S
G
V
T
T
V
S
P
R
A
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.9
81.8
52.2
N.A.
90.2
28.7
N.A.
47
29.3
23.7
52.7
N.A.
41.4
N.A.
N.A.
41.4
Protein Similarity:
100
62.5
84.2
61.3
N.A.
92.3
43.8
N.A.
52.5
45.8
40.5
62
N.A.
51.3
N.A.
N.A.
55.2
P-Site Identity:
100
13.3
20
13.3
N.A.
46.6
20
N.A.
13.3
33.3
26.6
13.3
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
33.3
20
33.3
N.A.
46.6
40
N.A.
13.3
40
40
33.3
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
34
9
17
9
9
0
34
0
42
9
9
25
0
% A
% Cys:
0
0
9
9
0
0
0
0
9
9
0
0
0
0
0
% C
% Asp:
9
17
0
17
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
9
0
9
9
0
17
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% F
% Gly:
0
9
0
0
0
9
9
9
0
0
0
9
9
0
9
% G
% His:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
9
9
0
9
0
0
0
0
0
17
0
0
% I
% Lys:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
17
0
0
0
0
0
0
0
17
0
0
17
0
0
% L
% Met:
0
0
0
9
9
9
0
0
0
0
0
0
0
0
9
% M
% Asn:
17
0
0
0
17
9
0
0
0
0
0
0
9
0
9
% N
% Pro:
34
9
0
25
0
42
50
9
17
17
9
59
17
9
34
% P
% Gln:
0
9
0
0
0
0
0
0
0
9
0
9
9
0
0
% Q
% Arg:
0
0
0
9
9
0
0
9
0
0
0
17
9
0
9
% R
% Ser:
0
0
9
0
34
17
0
17
17
17
34
0
0
50
17
% S
% Thr:
9
0
0
9
0
0
0
42
25
0
0
0
0
0
0
% T
% Val:
0
25
9
9
0
0
9
0
0
9
17
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
17
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _