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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WRN
All Species:
21.52
Human Site:
S1122
Identified Species:
43.03
UniProt:
Q14191
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14191
NP_000544.2
1432
162495
S1122
C
D
K
I
S
S
G
S
N
I
S
K
K
S
I
Chimpanzee
Pan troglodytes
XP_528104
1432
162383
S1122
C
D
K
I
S
S
G
S
N
I
S
K
K
S
I
Rhesus Macaque
Macaca mulatta
XP_001085031
1432
162219
S1122
C
D
K
V
S
S
G
S
N
I
S
K
K
S
I
Dog
Lupus familis
XP_539984
1680
188955
S1320
S
D
K
I
S
S
G
S
N
I
P
E
K
S
I
Cat
Felis silvestris
Mouse
Mus musculus
O09053
1401
157269
T1087
P
E
K
V
S
S
G
T
N
I
P
K
K
S
A
Rat
Rattus norvegicus
XP_001059940
1400
157256
S1087
P
E
K
F
S
S
G
S
N
I
P
K
K
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508312
1813
203868
N1477
A
E
K
I
S
S
R
N
K
S
D
M
M
Q
L
Chicken
Gallus gallus
Q9I920
1142
126164
A851
M
V
D
I
F
L
G
A
E
S
A
K
I
H
S
Frog
Xenopus laevis
O93530
1436
161833
A1070
A
E
R
L
S
K
A
A
G
V
S
K
S
S
F
Zebra Danio
Brachydanio rerio
XP_697980
1361
152386
A1070
D
L
P
S
R
S
A
A
R
Q
T
Q
I
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19546
1056
118504
S765
P
G
A
S
R
S
Q
S
T
K
S
S
T
E
I
Sea Urchin
Strong. purpuratus
XP_001184484
1274
143807
G983
F
P
S
V
F
T
G
G
V
S
I
V
I
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.1
64.5
N.A.
70.2
69.5
N.A.
41.7
22.9
52.1
45.8
N.A.
N.A.
N.A.
25.4
20.3
Protein Similarity:
100
99.3
97.2
72.6
N.A.
81.8
81.2
N.A.
56.5
38.3
70
63.7
N.A.
N.A.
N.A.
41.8
38.8
P-Site Identity:
100
100
93.3
80
N.A.
60
66.6
N.A.
26.6
20
26.6
6.6
N.A.
N.A.
N.A.
26.6
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
46.6
33.3
60
26.6
N.A.
N.A.
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
0
0
17
25
0
0
9
0
0
0
9
% A
% Cys:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
34
9
0
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
34
0
0
0
0
0
0
9
0
0
9
0
9
0
% E
% Phe:
9
0
0
9
17
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
9
0
0
0
0
67
9
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
42
0
0
0
0
0
50
9
0
25
0
42
% I
% Lys:
0
0
59
0
0
9
0
0
9
9
0
59
50
0
0
% K
% Leu:
0
9
0
9
0
9
0
0
0
0
0
0
0
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
50
0
0
0
0
0
0
% N
% Pro:
25
9
9
0
0
0
0
0
0
0
25
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
9
0
0
9
0
9
0
17
0
% Q
% Arg:
0
0
9
0
17
0
9
0
9
0
0
0
0
0
0
% R
% Ser:
9
0
9
17
67
75
0
50
0
25
42
9
9
67
9
% S
% Thr:
0
0
0
0
0
9
0
9
9
0
9
0
9
0
9
% T
% Val:
0
9
0
25
0
0
0
0
9
9
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _