KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WRN
All Species:
5.15
Human Site:
Y736
Identified Species:
10.3
UniProt:
Q14191
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14191
NP_000544.2
1432
162495
Y736
G
F
D
R
P
N
L
Y
L
E
V
R
R
K
T
Chimpanzee
Pan troglodytes
XP_528104
1432
162383
Y736
G
F
D
R
P
N
L
Y
L
E
V
R
R
K
T
Rhesus Macaque
Macaca mulatta
XP_001085031
1432
162219
L736
F
D
R
P
N
L
Y
L
E
V
R
R
K
T
G
Dog
Lupus familis
XP_539984
1680
188955
L933
F
D
R
P
N
L
Y
L
E
V
R
R
K
T
G
Cat
Felis silvestris
Mouse
Mus musculus
O09053
1401
157269
L701
F
D
R
P
N
L
Y
L
E
V
G
R
K
T
G
Rat
Rattus norvegicus
XP_001059940
1400
157256
L701
F
D
R
P
N
L
Y
L
E
V
E
R
K
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508312
1813
203868
L1091
F
D
R
P
N
L
Y
L
E
V
G
R
K
T
G
Chicken
Gallus gallus
Q9I920
1142
126164
S484
S
K
T
Y
M
Q
L
S
K
K
D
P
I
I
K
Frog
Xenopus laevis
O93530
1436
161833
D679
D
R
P
N
L
Y
L
D
V
A
R
K
T
T
N
Zebra Danio
Brachydanio rerio
XP_697980
1361
152386
L632
F
D
R
P
N
L
Y
L
D
V
N
R
K
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19546
1056
118504
A398
R
V
R
D
D
V
I
A
N
L
R
L
R
K
P
Sea Urchin
Strong. purpuratus
XP_001184484
1274
143807
L616
S
N
V
A
P
G
S
L
T
V
I
S
S
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.1
64.5
N.A.
70.2
69.5
N.A.
41.7
22.9
52.1
45.8
N.A.
N.A.
N.A.
25.4
20.3
Protein Similarity:
100
99.3
97.2
72.6
N.A.
81.8
81.2
N.A.
56.5
38.3
70
63.7
N.A.
N.A.
N.A.
41.8
38.8
P-Site Identity:
100
100
6.6
6.6
N.A.
6.6
6.6
N.A.
6.6
6.6
6.6
6.6
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
13.3
13.3
N.A.
13.3
13.3
N.A.
13.3
13.3
20
13.3
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
9
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
50
17
9
9
0
0
9
9
0
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
42
17
9
0
0
0
0
% E
% Phe:
50
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
9
0
0
0
0
17
0
0
0
59
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
9
0
9
9
0
% I
% Lys:
0
9
0
0
0
0
0
0
9
9
0
9
50
25
9
% K
% Leu:
0
0
0
0
9
50
34
59
17
9
0
9
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
9
50
17
0
0
9
0
9
0
0
0
9
% N
% Pro:
0
0
9
50
25
0
0
0
0
0
0
9
0
9
9
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
9
59
17
0
0
0
0
0
0
34
67
25
0
0
% R
% Ser:
17
0
0
0
0
0
9
9
0
0
0
9
9
9
0
% S
% Thr:
0
0
9
0
0
0
0
0
9
0
0
0
9
50
17
% T
% Val:
0
9
9
0
0
9
0
0
9
59
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
9
50
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _