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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ICT1 All Species: 23.7
Human Site: S200 Identified Species: 37.24
UniProt: Q14197 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14197 NP_001536.1 206 23630 S200 I H S A V K T S R R V D M D _
Chimpanzee Pan troglodytes XP_001138419 206 23643 S200 I H S A V K T S R R V D M D _
Rhesus Macaque Macaca mulatta XP_001092083 206 23638 S200 I H S A V K T S R R V D M D _
Dog Lupus familis XP_533118 161 18501
Cat Felis silvestris
Mouse Mus musculus Q8R035 206 23458 S200 L N S A L K T S R R M T M D _
Rat Rattus norvegicus XP_221110 206 23451 S200 I N S T I K T S R R M T M D _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516100 144 16353 S138 I T A T I K A S R R A D V D _
Chicken Gallus gallus XP_420117 194 21944 S188 I H S N I K Q S R K A D F D _
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922710 193 21697 A187 I H S A T K R A R R P D F D _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609416 203 22777 D194 G R A Q V K A D R Q G P S G L
Honey Bee Apis mellifera XP_393856 198 22969 F191 K H S M I K Q F K K A P M D F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001179942 139 15641
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001148646 227 24898 F219 V L S Q K K E F R R N R T S W
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001077760 236 26053 A227 V L S D K K S A R R S R G S Y
Baker's Yeast Sacchar. cerevisiae Q12322 202 23171 N194 V H S D K K K N R S K I K F N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 94.1 64.5 N.A. 79.6 80 N.A. 50 59.7 N.A. 42.2 N.A. 38.3 37.3 N.A. 33
Protein Similarity: 100 99.5 96.5 71.8 N.A. 88.8 89.3 N.A. 61.6 71.3 N.A. 59.7 N.A. 56.3 56.3 N.A. 43.6
P-Site Identity: 100 100 100 0 N.A. 64.2 64.2 N.A. 50 57.1 N.A. 64.2 N.A. 20 33.3 N.A. 0
P-Site Similarity: 100 100 100 0 N.A. 92.8 85.7 N.A. 71.4 71.4 N.A. 71.4 N.A. 33.3 53.3 N.A. 0
Percent
Protein Identity: N.A. 33 N.A. 30 27.6 N.A.
Protein Similarity: N.A. 49.7 N.A. 51.6 49.5 N.A.
P-Site Identity: N.A. 26.6 N.A. 26.6 26.6 N.A.
P-Site Similarity: N.A. 33.3 N.A. 53.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 34 0 0 14 14 0 0 20 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 14 0 0 0 7 0 0 0 40 0 60 0 % D
% Glu: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 14 0 0 0 0 14 7 7 % F
% Gly: 7 0 0 0 0 0 0 0 0 0 7 0 7 7 0 % G
% His: 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 47 0 0 0 27 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 7 0 0 0 20 87 7 0 7 14 7 0 7 0 0 % K
% Leu: 7 14 0 0 7 0 0 0 0 0 0 0 0 0 7 % L
% Met: 0 0 0 7 0 0 0 0 0 0 14 0 40 0 0 % M
% Asn: 0 14 0 7 0 0 0 7 0 0 7 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 7 14 0 0 0 % P
% Gln: 0 0 0 14 0 0 14 0 0 7 0 0 0 0 0 % Q
% Arg: 0 7 0 0 0 0 7 0 80 60 0 14 0 0 0 % R
% Ser: 0 0 74 0 0 0 7 47 0 7 7 0 7 14 0 % S
% Thr: 0 7 0 14 7 0 34 0 0 0 0 14 7 0 0 % T
% Val: 20 0 0 0 27 0 0 0 0 0 20 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54 % _