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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICT1
All Species:
13.33
Human Site:
S52
Identified Species:
20.95
UniProt:
Q14197
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14197
NP_001536.1
206
23630
S52
L
D
K
L
Y
P
E
S
Q
G
S
D
T
A
W
Chimpanzee
Pan troglodytes
XP_001138419
206
23643
S52
L
D
K
L
Y
P
E
S
Q
G
S
D
T
A
W
Rhesus Macaque
Macaca mulatta
XP_001092083
206
23638
F52
L
D
K
L
Y
P
E
F
Q
G
S
D
T
A
W
Dog
Lupus familis
XP_533118
161
18501
K21
R
D
T
E
D
D
A
K
Q
A
N
N
D
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R035
206
23458
S52
L
D
K
L
Y
P
E
S
K
G
A
D
T
A
W
Rat
Rattus norvegicus
XP_221110
206
23451
S52
L
D
K
L
Y
P
E
S
K
G
V
D
T
A
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516100
144
16353
Chicken
Gallus gallus
XP_420117
194
21944
R42
L
D
K
L
Y
P
P
R
D
G
G
T
A
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922710
193
21697
R45
G
I
G
F
C
P
A
R
A
A
A
R
S
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609416
203
22777
R45
D
K
I
Y
P
G
A
R
L
Q
I
Y
T
P
P
Honey Bee
Apis mellifera
XP_393856
198
22969
I43
K
L
Y
P
T
H
S
I
K
L
F
T
P
T
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179942
139
15641
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148646
227
24898
Q71
A
R
L
A
L
T
Q
Q
V
L
R
N
A
E
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001077760
236
26053
Q79
S
R
L
S
Q
V
Q
Q
M
L
H
E
A
E
E
Baker's Yeast
Sacchar. cerevisiae
Q12322
202
23171
G44
L
I
S
N
K
K
I
G
K
K
S
D
F
V
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.1
64.5
N.A.
79.6
80
N.A.
50
59.7
N.A.
42.2
N.A.
38.3
37.3
N.A.
33
Protein Similarity:
100
99.5
96.5
71.8
N.A.
88.8
89.3
N.A.
61.6
71.3
N.A.
59.7
N.A.
56.3
56.3
N.A.
43.6
P-Site Identity:
100
100
93.3
13.3
N.A.
86.6
86.6
N.A.
0
46.6
N.A.
6.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
93.3
26.6
N.A.
100
93.3
N.A.
0
53.3
N.A.
20
N.A.
6.6
13.3
N.A.
0
Percent
Protein Identity:
N.A.
33
N.A.
30
27.6
N.A.
Protein Similarity:
N.A.
49.7
N.A.
51.6
49.5
N.A.
P-Site Identity:
N.A.
0
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
20
0
7
14
14
0
20
34
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
47
0
0
7
7
0
0
7
0
0
40
7
0
7
% D
% Glu:
0
0
0
7
0
0
34
0
0
0
0
7
0
14
14
% E
% Phe:
0
0
0
7
0
0
0
7
0
0
7
0
7
0
7
% F
% Gly:
7
0
7
0
0
7
0
7
0
40
7
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
14
7
0
0
0
7
7
0
0
7
0
0
7
0
% I
% Lys:
7
7
40
0
7
7
0
7
27
7
0
0
0
0
0
% K
% Leu:
47
7
14
40
7
0
0
0
7
20
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
7
14
0
0
0
% N
% Pro:
0
0
0
7
7
47
7
0
0
0
0
0
7
7
14
% P
% Gln:
0
0
0
0
7
0
14
14
27
7
0
0
0
0
14
% Q
% Arg:
7
14
0
0
0
0
0
20
0
0
7
7
0
0
0
% R
% Ser:
7
0
7
7
0
0
7
27
0
0
27
0
7
7
0
% S
% Thr:
0
0
7
0
7
7
0
0
0
0
0
14
40
14
0
% T
% Val:
0
0
0
0
0
7
0
0
7
0
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% W
% Tyr:
0
0
7
7
40
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _