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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICT1
All Species:
12.42
Human Site:
T164
Identified Species:
19.52
UniProt:
Q14197
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14197
NP_001536.1
206
23630
T164
M
I
T
E
A
S
Q
T
P
K
E
P
T
K
E
Chimpanzee
Pan troglodytes
XP_001138419
206
23643
T164
M
I
T
E
A
S
Q
T
P
K
E
P
T
K
E
Rhesus Macaque
Macaca mulatta
XP_001092083
206
23638
T164
M
I
A
E
A
S
E
T
P
K
E
P
T
K
E
Dog
Lupus familis
XP_533118
161
18501
H131
S
K
E
D
A
L
L
H
R
L
R
I
E
N
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8R035
206
23458
V164
M
I
A
E
A
S
Q
V
P
K
E
P
S
K
E
Rat
Rattus norvegicus
XP_221110
206
23451
V164
M
I
A
K
A
S
Q
V
P
K
E
P
S
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516100
144
16353
Q113
P
S
K
E
T
K
E
Q
H
R
L
R
V
E
K
Chicken
Gallus gallus
XP_420117
194
21944
K152
M
V
T
E
A
T
E
K
P
K
V
V
S
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922710
193
21697
S156
E
Q
Q
E
A
E
P
S
P
E
D
Q
E
L
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609416
203
22777
A158
I
R
S
Q
E
A
V
A
P
A
P
P
S
E
E
Honey Bee
Apis mellifera
XP_393856
198
22969
P155
T
I
W
E
A
T
K
P
P
P
E
T
S
P
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179942
139
15641
D109
S
Q
I
R
N
F
S
D
C
L
Q
K
I
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148646
227
24898
V183
I
I
D
A
A
S
Y
V
P
P
P
P
T
E
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001077760
236
26053
V191
I
I
D
A
A
S
Y
V
P
P
P
P
S
E
E
Baker's Yeast
Sacchar. cerevisiae
Q12322
202
23171
T162
T
C
Q
F
P
N
D
T
T
A
E
T
S
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.1
64.5
N.A.
79.6
80
N.A.
50
59.7
N.A.
42.2
N.A.
38.3
37.3
N.A.
33
Protein Similarity:
100
99.5
96.5
71.8
N.A.
88.8
89.3
N.A.
61.6
71.3
N.A.
59.7
N.A.
56.3
56.3
N.A.
43.6
P-Site Identity:
100
100
86.6
6.6
N.A.
80
73.3
N.A.
6.6
53.3
N.A.
20
N.A.
20
40
N.A.
0
P-Site Similarity:
100
100
93.3
13.3
N.A.
86.6
86.6
N.A.
33.3
80
N.A.
40
N.A.
60
60
N.A.
20
Percent
Protein Identity:
N.A.
33
N.A.
30
27.6
N.A.
Protein Similarity:
N.A.
49.7
N.A.
51.6
49.5
N.A.
P-Site Identity:
N.A.
40
N.A.
40
20
N.A.
P-Site Similarity:
N.A.
60
N.A.
60
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
14
74
7
0
7
0
14
0
0
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
14
7
0
0
7
7
0
0
7
0
0
0
14
% D
% Glu:
7
0
7
54
7
7
20
0
0
7
47
0
14
27
60
% E
% Phe:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
20
54
7
0
0
0
0
0
0
0
0
7
7
0
0
% I
% Lys:
0
7
7
7
0
7
7
7
0
40
0
7
0
47
14
% K
% Leu:
0
0
0
0
0
7
7
0
0
14
7
0
0
7
0
% L
% Met:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
7
7
0
0
0
0
0
0
0
7
0
% N
% Pro:
7
0
0
0
7
0
7
7
74
20
20
54
0
7
0
% P
% Gln:
0
14
14
7
0
0
27
7
0
0
7
7
0
0
0
% Q
% Arg:
0
7
0
7
0
0
0
0
7
7
7
7
0
7
0
% R
% Ser:
14
7
7
0
0
47
7
7
0
0
0
0
47
0
0
% S
% Thr:
14
0
20
0
7
14
0
27
7
0
0
14
27
0
0
% T
% Val:
0
7
0
0
0
0
7
27
0
0
7
7
7
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _