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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DYNC1H1 All Species: 27.27
Human Site: Y1283 Identified Species: 50
UniProt: Q14204 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14204 NP_001367.2 4646 532408 Y1283 A L Q A L T I Y E G K F G R L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112455 4147 474593 V1141 E V L F K T P V S I T E H P K
Dog Lupus familis XP_537556 4646 532374 Y1283 A L Q A L T I Y E G K F G R L
Cat Felis silvestris
Mouse Mus musculus Q9JHU4 4644 532007 Y1281 A L Q A L T I Y E G K F G R L
Rat Rattus norvegicus P38650 4644 532233 Y1281 A L Q A L T I Y E G K F G R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512683 4644 532495 Y1281 A L Q A L T I Y E G K F G R L
Chicken Gallus gallus XP_421371 4617 529846 Y1250 A L Q A L T I Y E G K F G R L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001036210 4643 533172 Y1282 A L Q S L T I Y E G K F G R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P37276 4639 530166 F1273 A L Q Q L Q I F E S K Y S R L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19020 4568 521560 F1250 A L N V I T A F E A K L N K L
Sea Urchin Strong. purpuratus XP_797645 4652 531803 F1283 A T N S L W I F E G K F T R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36022 4092 471329 H1114 L K V R F P S H F V Y I D Q L
Red Bread Mold Neurospora crassa P45443 4367 495560 F1330 A S A T L T H F E Q R I T K L
Conservation
Percent
Protein Identity: 100 N.A. 83.9 99.2 N.A. 99 98.5 N.A. 98.4 95.5 N.A. 90.9 N.A. 71.9 N.A. 55.6 74.5
Protein Similarity: 100 N.A. 84.5 99.6 N.A. 99.4 99.2 N.A. 99.4 97.1 N.A. 95.8 N.A. 85.2 N.A. 73.3 86.2
P-Site Identity: 100 N.A. 6.6 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 N.A. 60 N.A. 40 60
P-Site Similarity: 100 N.A. 13.3 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 73.3 N.A. 60 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.8 49.8
Protein Similarity: N.A. N.A. N.A. N.A. 48.9 67.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. 20 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 85 0 8 47 0 0 8 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 85 0 0 8 0 0 0 % E
% Phe: 0 0 0 8 8 0 0 31 8 0 0 62 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 62 0 0 54 0 0 % G
% His: 0 0 0 0 0 0 8 8 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 8 0 70 0 0 8 0 16 0 0 0 % I
% Lys: 0 8 0 0 8 0 0 0 0 0 77 0 0 16 8 % K
% Leu: 8 70 8 0 77 0 0 0 0 0 0 8 0 0 93 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 16 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 8 8 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 62 8 0 8 0 0 0 8 0 0 0 8 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 8 0 0 70 0 % R
% Ser: 0 8 0 16 0 0 8 0 8 8 0 0 8 0 0 % S
% Thr: 0 8 0 8 0 77 0 0 0 0 8 0 16 0 0 % T
% Val: 0 8 8 8 0 0 0 8 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 54 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _