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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYNC1H1
All Species:
24.24
Human Site:
Y221
Identified Species:
44.44
UniProt:
Q14204
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14204
NP_001367.2
4646
532408
Y221
T
N
V
A
K
Q
C
Y
E
R
G
E
K
P
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112455
4147
474593
L225
K
A
H
Q
A
N
Q
L
Y
P
F
A
I
S
L
Dog
Lupus familis
XP_537556
4646
532374
Y221
T
N
V
A
K
Q
C
Y
E
R
G
E
K
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHU4
4644
532007
Y219
T
N
V
A
K
Q
C
Y
E
R
G
E
K
P
K
Rat
Rattus norvegicus
P38650
4644
532233
Y219
T
N
V
A
K
Q
C
Y
E
R
G
E
K
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512683
4644
532495
Y219
T
N
V
A
K
Q
C
Y
E
R
G
E
K
P
K
Chicken
Gallus gallus
XP_421371
4617
529846
Q224
N
R
W
I
R
E
I
Q
K
V
T
K
L
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036210
4643
533172
Y220
S
N
V
A
K
Q
C
Y
E
R
G
E
K
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37276
4639
530166
A221
N
N
V
I
R
K
C
A
E
E
N
R
K
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19020
4568
521560
G217
L
D
A
I
E
Q
A
G
K
E
N
R
R
A
K
Sea Urchin
Strong. purpuratus
XP_797645
4652
531803
G218
S
T
M
I
R
K
C
G
D
E
G
R
K
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36022
4092
471329
G198
I
K
L
A
V
S
K
G
A
T
S
H
D
Y
A
Red Bread Mold
Neurospora crassa
P45443
4367
495560
T253
S
T
L
E
E
A
A
T
K
N
V
K
P
S
I
Conservation
Percent
Protein Identity:
100
N.A.
83.9
99.2
N.A.
99
98.5
N.A.
98.4
95.5
N.A.
90.9
N.A.
71.9
N.A.
55.6
74.5
Protein Similarity:
100
N.A.
84.5
99.6
N.A.
99.4
99.2
N.A.
99.4
97.1
N.A.
95.8
N.A.
85.2
N.A.
73.3
86.2
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
100
0
N.A.
93.3
N.A.
40
N.A.
13.3
33.3
P-Site Similarity:
100
N.A.
0
100
N.A.
100
100
N.A.
100
33.3
N.A.
100
N.A.
53.3
N.A.
40
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
49.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
67.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
54
8
8
16
8
8
0
0
8
0
16
8
% A
% Cys:
0
0
0
0
0
0
62
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
8
0
0
0
8
8
0
% D
% Glu:
0
0
0
8
16
8
0
0
54
24
0
47
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
24
0
0
54
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
0
31
0
0
8
0
0
0
0
0
8
0
8
% I
% Lys:
8
8
0
0
47
16
8
0
24
0
0
16
62
0
70
% K
% Leu:
8
0
16
0
0
0
0
8
0
0
0
0
8
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
54
0
0
0
8
0
0
0
8
16
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
8
54
0
% P
% Gln:
0
0
0
8
0
54
8
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
24
0
0
0
0
47
0
24
8
0
8
% R
% Ser:
24
0
0
0
0
8
0
0
0
0
8
0
0
16
0
% S
% Thr:
39
16
0
0
0
0
0
8
0
8
8
0
0
0
0
% T
% Val:
0
0
54
0
8
0
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _