KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAT
All Species:
13.03
Human Site:
S422
Identified Species:
31.85
UniProt:
Q14207
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14207
NP_002510.2
1427
154291
S422
N
F
S
Q
I
S
T
S
I
Q
K
K
A
F
K
Chimpanzee
Pan troglodytes
XP_508739
1427
154232
S422
N
F
S
Q
I
S
T
S
I
Q
K
K
A
F
K
Rhesus Macaque
Macaca mulatta
XP_001104186
1427
154423
S421
N
F
S
Q
I
S
A
S
V
Q
K
K
A
F
K
Dog
Lupus familis
XP_546538
1450
156698
S431
H
F
S
Q
I
G
S
S
I
Q
K
K
A
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMA5
1420
152157
N416
L
P
Q
E
S
Q
E
N
F
S
Q
I
S
S
N
Rat
Rattus norvegicus
NP_001101617
1415
151589
P411
G
N
N
H
D
V
L
P
Q
E
S
Q
G
N
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508521
1076
109024
N87
G
A
S
C
A
L
K
N
G
G
S
D
D
R
L
Chicken
Gallus gallus
XP_417161
1559
168410
R536
E
Q
L
H
G
N
C
R
L
R
K
E
A
D
V
Frog
Xenopus laevis
A2RRX6
1356
145650
H368
G
V
A
T
T
S
I
H
V
A
N
D
N
L
E
Zebra Danio
Brachydanio rerio
XP_690976
1310
139914
I322
T
D
D
A
I
Q
D
I
L
A
Q
T
E
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.9
77.6
N.A.
74.8
74.3
N.A.
30.8
48.1
35.7
32.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.7
85.3
N.A.
83.8
83.4
N.A.
43.3
62.3
52.5
48.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
0
0
N.A.
6.6
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
26.6
20
N.A.
13.3
40
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
10
0
10
0
0
20
0
0
50
0
0
% A
% Cys:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
10
0
10
0
0
0
0
20
10
10
10
% D
% Glu:
10
0
0
10
0
0
10
0
0
10
0
10
10
0
10
% E
% Phe:
0
40
0
0
0
0
0
0
10
0
0
0
0
40
10
% F
% Gly:
30
0
0
0
10
10
0
0
10
10
0
0
10
0
0
% G
% His:
10
0
0
20
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
50
0
10
10
30
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
50
40
0
0
40
% K
% Leu:
10
0
10
0
0
10
10
0
20
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
30
10
10
0
0
10
0
20
0
0
10
0
10
10
10
% N
% Pro:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
10
10
40
0
20
0
0
10
40
20
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
0
0
0
10
0
% R
% Ser:
0
0
50
0
10
40
10
40
0
10
20
0
10
20
0
% S
% Thr:
10
0
0
10
10
0
20
0
0
0
0
10
0
0
0
% T
% Val:
0
10
0
0
0
10
0
0
20
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _