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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EBI3 All Species: 5.15
Human Site: S86 Identified Species: 16.19
UniProt: Q14213 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14213 NP_005746.2 229 25396 S86 C L Q Q T P T S T S C T I T D
Chimpanzee Pan troglodytes XP_001138182 229 25408 S86 C L Q Q T P T S T S C T I T D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542161 229 25286 A86 C L Q Q T P E A T S C T I P D
Cat Felis silvestris
Mouse Mus musculus O35228 228 25335 S86 L Q R S P Q A S R C T I P D V
Rat Rattus norvegicus Q08406 372 40804 K161 C E K D P A L K N R C H I R Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P51641 362 40289 K159 C E K D I F P K N R C H I R Y
Frog Xenopus laevis NP_001080560 396 44902 K190 C E K D P F P K N R C H I K Y
Zebra Danio Brachydanio rerio NP_001106980 302 33449 D156 C Q K W G D Q D R Q C A L E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. 69 N.A. 60.7 20.1 N.A. N.A. 23.2 21.7 28.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 N.A. 76.4 N.A. 73.3 33 N.A. N.A. 33.9 34.3 44.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 80 N.A. 6.6 20 N.A. N.A. 20 20 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 86.6 N.A. 13.3 26.6 N.A. N.A. 26.6 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 13 13 13 0 0 0 13 0 0 0 % A
% Cys: 88 0 0 0 0 0 0 0 0 13 88 0 0 0 0 % C
% Asp: 0 0 0 38 0 13 0 13 0 0 0 0 0 13 38 % D
% Glu: 0 38 0 0 0 0 13 0 0 0 0 0 0 13 13 % E
% Phe: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 38 0 0 0 % H
% Ile: 0 0 0 0 13 0 0 0 0 0 0 13 75 0 0 % I
% Lys: 0 0 50 0 0 0 0 38 0 0 0 0 0 13 0 % K
% Leu: 13 38 0 0 0 0 13 0 0 0 0 0 13 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 38 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 38 38 25 0 0 0 0 0 13 13 0 % P
% Gln: 0 25 38 38 0 13 13 0 0 13 0 0 0 0 0 % Q
% Arg: 0 0 13 0 0 0 0 0 25 38 0 0 0 25 0 % R
% Ser: 0 0 0 13 0 0 0 38 0 38 0 0 0 0 0 % S
% Thr: 0 0 0 0 38 0 25 0 38 0 13 38 0 25 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % V
% Trp: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 38 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _