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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EBI3
All Species:
10.91
Human Site:
Y165
Identified Species:
34.29
UniProt:
Q14213
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14213
NP_005746.2
229
25396
Y165
P
E
I
F
S
L
K
Y
W
I
R
Y
K
R
Q
Chimpanzee
Pan troglodytes
XP_001138182
229
25408
Y165
P
E
I
F
S
L
K
Y
W
I
R
Y
K
R
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542161
229
25286
Y165
P
E
L
F
S
L
K
Y
W
I
R
Y
K
H
H
Cat
Felis silvestris
Mouse
Mus musculus
O35228
228
25335
L165
I
F
S
L
K
Y
R
L
R
Y
R
R
R
G
A
Rat
Rattus norvegicus
Q08406
372
40804
F242
P
E
S
F
P
L
K
F
F
L
R
Y
R
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P51641
362
40289
F240
P
E
S
F
P
L
K
F
F
L
R
Y
R
P
L
Frog
Xenopus laevis
NP_001080560
396
44902
F271
A
D
S
F
P
L
K
F
F
L
R
Y
R
P
L
Zebra Danio
Brachydanio rerio
NP_001106980
302
33449
Y235
P
V
N
F
L
L
K
Y
K
V
R
F
H
W
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
69
N.A.
60.7
20.1
N.A.
N.A.
23.2
21.7
28.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
N.A.
76.4
N.A.
73.3
33
N.A.
N.A.
33.9
34.3
44.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
80
N.A.
6.6
46.6
N.A.
N.A.
46.6
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
86.6
N.A.
20
73.3
N.A.
N.A.
73.3
66.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
63
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
13
0
88
0
0
0
38
38
0
0
13
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
13
13
% H
% Ile:
13
0
25
0
0
0
0
0
0
38
0
0
0
0
0
% I
% Lys:
0
0
0
0
13
0
88
0
13
0
0
0
38
0
0
% K
% Leu:
0
0
13
13
13
88
0
13
0
38
0
0
0
0
38
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
75
0
0
0
38
0
0
0
0
0
0
0
0
38
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% Q
% Arg:
0
0
0
0
0
0
13
0
13
0
100
13
50
25
0
% R
% Ser:
0
0
50
0
38
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
38
0
0
0
0
13
0
% W
% Tyr:
0
0
0
0
0
13
0
50
0
13
0
75
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _