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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2B1
All Species:
0
Human Site:
S105
Identified Species:
0
UniProt:
Q14232
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14232
NP_001405.1
305
33712
S105
E
L
F
L
R
R
I
S
L
S
R
N
K
I
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101480
305
33696
Dog
Lupus familis
XP_534645
305
33854
Cat
Felis silvestris
Mouse
Mus musculus
Q99LC8
305
33798
Rat
Rattus norvegicus
Q64270
305
33660
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507558
316
34903
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084600
302
33557
Zebra Danio
Brachydanio rerio
XP_002662251
302
33553
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651752
306
34376
Honey Bee
Apis mellifera
XP_392643
301
33602
Nematode Worm
Caenorhab. elegans
P34604
305
34099
Sea Urchin
Strong. purpuratus
XP_783380
304
33798
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14741
305
34007
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
96.3
N.A.
94
92.7
N.A.
88.2
N.A.
78
76.3
N.A.
49.6
53.4
43.2
59.3
Protein Similarity:
100
N.A.
99.3
97.3
N.A.
96.7
95
N.A.
92.7
N.A.
88.5
87.2
N.A.
67.6
75.7
63.9
75.7
P-Site Identity:
100
N.A.
0
0
N.A.
0
0
N.A.
0
N.A.
0
0
N.A.
0
0
0
0
P-Site Similarity:
100
N.A.
0
0
N.A.
0
0
N.A.
0
N.A.
0
0
N.A.
0
0
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
59.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
100
0
0
0
0
0
0
100
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% K
% Leu:
0
100
0
100
0
0
0
0
100
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
100
100
0
0
0
0
100
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
100
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _