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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTTN All Species: 16.97
Human Site: Y453 Identified Species: 33.94
UniProt: Q14247 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14247 NP_005222.2 550 61586 Y453 Y S M E A A D Y R E A S S Q Q
Chimpanzee Pan troglodytes XP_508613 542 59878 Y445 Y S M E A A D Y R E A S S Q Q
Rhesus Macaque Macaca mulatta XP_001100193 550 61624 Y453 Y S V E A A D Y R E A G S Q Q
Dog Lupus familis XP_851317 541 60553 Y444 Y S M E A A D Y Q D A S S Q Q
Cat Felis silvestris
Mouse Mus musculus Q60598 546 61241 I449 Y S I E A A G I P E A G S Q Q
Rat Rattus norvegicus Q9JHL4 436 48594 P343 D E P T Y E V P S E Q E T L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507265 462 52591 I369 H S D Y Q E A I S Q Q E L A Y
Chicken Gallus gallus Q01406 563 63311 Y466 Y K T T G S D Y Q E A V S Q R
Frog Xenopus laevis Q6GM14 376 42749 Q283 P E Q F T A S Q Q E E E N I Y
Zebra Danio Brachydanio rerio NP_001004121 504 56595 E410 E D G S H V Y E L E Q H A A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VU84 531 58711 S433 E E V R T K V S V T V Q Q S Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999782 587 64904 Q488 Q P P D D M G Q Q T Y E E V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 98.3 90.5 N.A. 92.1 23.8 N.A. 64.9 83.4 26.7 68 N.A. 21.4 N.A. N.A. 46.5
Protein Similarity: 100 91 99 94.1 N.A. 95 40.1 N.A. 74.1 90 41.2 80 N.A. 38 N.A. N.A. 59.8
P-Site Identity: 100 100 86.6 86.6 N.A. 66.6 6.6 N.A. 6.6 46.6 13.3 6.6 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 100 N.A. 73.3 13.3 N.A. 20 66.6 26.6 20 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 42 50 9 0 0 0 50 0 9 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 9 9 9 0 42 0 0 9 0 0 0 0 9 % D
% Glu: 17 25 0 42 0 17 0 9 0 67 9 34 9 0 9 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 9 0 17 0 0 0 0 17 0 0 0 % G
% His: 9 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 17 0 0 0 0 0 9 0 % I
% Lys: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 9 0 0 0 9 9 0 % L
% Met: 0 0 25 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 9 9 17 0 0 0 0 9 9 0 0 0 0 0 0 % P
% Gln: 9 0 9 0 9 0 0 17 34 9 25 9 9 50 50 % Q
% Arg: 0 0 0 9 0 0 0 0 25 0 0 0 0 0 9 % R
% Ser: 0 50 0 9 0 9 9 9 17 0 0 25 50 9 0 % S
% Thr: 0 0 9 17 17 0 0 0 0 17 0 0 9 0 0 % T
% Val: 0 0 17 0 0 9 17 0 9 0 9 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 50 0 0 9 9 0 9 42 0 0 9 0 0 0 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _