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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTTN All Species: 29.39
Human Site: Y503 Identified Species: 58.79
UniProt: Q14247 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14247 NP_005222.2 550 61586 Y503 T A V A L Y D Y Q A A G D D E
Chimpanzee Pan troglodytes XP_508613 542 59878 Y495 T A V A L Y D Y Q A A G D D E
Rhesus Macaque Macaca mulatta XP_001100193 550 61624 Y503 T A V A L Y D Y Q A A G D D E
Dog Lupus familis XP_851317 541 60553 Y494 T A V A L Y D Y Q A A G D D E
Cat Felis silvestris
Mouse Mus musculus Q60598 546 61241 Y499 T A I A L Y D Y Q A A G D D E
Rat Rattus norvegicus Q9JHL4 436 48594 D393 Y D Y Q A A D D T E I S F D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507265 462 52591 G419 L Y D Y Q A A G D D E I S F D
Chicken Gallus gallus Q01406 563 63311 Y516 T A I A L Y D Y Q A A G D D E
Frog Xenopus laevis Q6GM14 376 42749 D333 Y D Y Q A A D D T E I S F D P
Zebra Danio Brachydanio rerio NP_001004121 504 56595 A460 A L Y D Y Q A A G D D E I S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VU84 531 58711 Y483 R A R A L Y D Y Q A A D E T E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999782 587 64904 Y538 R A K A L Y D Y Q A T A E D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 98.3 90.5 N.A. 92.1 23.8 N.A. 64.9 83.4 26.7 68 N.A. 21.4 N.A. N.A. 46.5
Protein Similarity: 100 91 99 94.1 N.A. 95 40.1 N.A. 74.1 90 41.2 80 N.A. 38 N.A. N.A. 59.8
P-Site Identity: 100 100 100 100 N.A. 93.3 13.3 N.A. 0 93.3 13.3 0 N.A. 66.6 N.A. N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 6.6 100 13.3 0 N.A. 73.3 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 67 0 67 17 25 17 9 0 67 59 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 9 9 0 0 84 17 9 17 9 9 50 75 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 17 9 9 17 0 67 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 17 9 9 % F
% Gly: 0 0 0 0 0 0 0 9 9 0 0 50 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 17 0 0 0 0 0 0 0 17 9 9 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 9 0 0 67 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % P
% Gln: 0 0 0 17 9 9 0 0 67 0 0 0 0 0 0 % Q
% Arg: 17 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 17 9 9 0 % S
% Thr: 50 0 0 0 0 0 0 0 17 0 9 0 0 9 0 % T
% Val: 0 0 34 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 17 9 25 9 9 67 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _