KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENDOG
All Species:
27.88
Human Site:
Y182
Identified Species:
55.76
UniProt:
Q14249
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14249
NP_004426.2
297
32646
Y182
A
W
N
N
L
E
K
Y
S
R
S
L
T
R
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110294
299
32553
Y184
A
W
N
N
L
E
K
Y
S
R
S
L
T
R
S
Dog
Lupus familis
XP_851160
300
32804
Y185
A
W
N
N
L
E
K
Y
S
R
S
L
T
R
T
Cat
Felis silvestris
Mouse
Mus musculus
O08600
294
32172
Y179
A
W
N
N
L
E
R
Y
S
R
S
L
T
R
T
Rat
Rattus norvegicus
NP_001030110
294
32249
Y179
A
W
N
N
L
E
K
Y
S
R
S
L
T
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505874
136
15373
Y33
T
S
I
Y
K
N
V
Y
V
C
T
G
P
L
F
Chicken
Gallus gallus
XP_415487
301
33339
Y185
A
W
N
N
L
E
K
Y
S
R
S
L
A
R
R
Frog
Xenopus laevis
Q0IH72
358
40476
Y173
F
W
N
R
M
E
M
Y
C
R
D
L
T
K
R
Zebra Danio
Brachydanio rerio
Q502K1
343
39035
Y162
F
W
N
R
L
E
M
Y
C
R
E
L
T
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610737
310
34626
H197
A
W
N
T
L
E
A
H
V
R
R
L
T
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95NM6
308
34492
H190
K
W
N
D
L
E
M
H
C
R
R
V
A
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P08466
329
37191
F180
Y
W
A
H
L
E
Y
F
C
R
G
L
T
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.6
93.6
N.A.
90.2
89.5
N.A.
39
76
32.4
31.4
N.A.
49
N.A.
40.5
N.A.
Protein Similarity:
100
N.A.
96.3
95.3
N.A.
94.6
93.9
N.A.
40.7
81.7
48
47.5
N.A.
61.6
N.A.
58.4
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
93.3
N.A.
6.6
86.6
46.6
53.3
N.A.
53.3
N.A.
33.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
86.6
60
53.3
N.A.
73.3
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
9
0
0
0
9
0
0
0
0
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
34
9
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
92
0
0
0
0
9
0
0
9
0
% E
% Phe:
17
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% G
% His:
0
0
0
9
0
0
0
17
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
9
0
42
0
0
0
0
0
0
34
25
% K
% Leu:
0
0
0
0
84
0
0
0
0
0
0
84
0
9
0
% L
% Met:
0
0
0
0
9
0
25
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
84
50
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
17
0
0
9
0
0
92
17
0
0
50
17
% R
% Ser:
0
9
0
0
0
0
0
0
50
0
50
0
0
0
17
% S
% Thr:
9
0
0
9
0
0
0
0
0
0
9
0
75
0
34
% T
% Val:
0
0
0
0
0
0
9
0
17
0
0
9
0
0
0
% V
% Trp:
0
92
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
9
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _